171006-99-8

Basic information

• Product Name: 1,2,4-Oxadiazol-3-amine,5-propyl-(9CI)
• Synonyms: 1,2,4-Oxadiazol-3-amine,5-propyl-(9CI);5-propyl-1,2,4-oxadiazol-3-amine(SALTDATA: FREE);5-Propyl-1,2,4-oxadiazol-3-amine
• CAS NO: 171006-99-8
• Molecular Formula: C5H9N3O
• Molecular Weight: 127.14446
• Product Categories: AMINEPRIMARY
• Mol File: 171006-99-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,4-Oxadiazol-3-amine,5-propyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Oxadiazol-3-amine,5-propyl-(9CI)(171006-99-8)
• EPA Substance Registry System: 1,2,4-Oxadiazol-3-amine,5-propyl-(9CI)(171006-99-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 171006-99-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,2,4-Oxadiazol-3-amine,5-propyl-(9CI) is used as a pharmaceutical intermediate for the development of new drugs with diverse therapeutic activities. Its unique chemical and biological properties allow for the creation of molecules with specific therapeutic targets, making it a valuable asset in drug discovery.
Used in Organic Synthesis:
1,2,4-Oxadiazol-3-amine,5-propyl-(9CI) serves as a building block in organic synthesis, enabling the creation of various functional molecules with tailored properties. Its versatile structure allows for the synthesis of compounds with specific characteristics, making it a valuable component in the development of novel chemical entities for various applications.

Upstream product

• 13115-21-4 N-Hydroxyguanidine 
• 105-54-4 butanoic acid ethyl ester 
• 5634-65-1 n-butyrylcyanamide 
• 40483-47-4 5-methyl-[1,2,4]oxadiazol-3-ylamine 
• 141-75-3 butyryl chloride 
• 171006-91-0 3-butanoylamino-4-phenylfurazan 

Relevant articles and documents

9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers

Small molecule mGluR1 enhancers based on the lead compound (9H-xanthene-9-carbonyl)-carbamic acid butyl ester derived from random-screening hit diphenylacetyl-carbamic acid ethyl ester were designed and synthesized as useful pharmacological tools for the study of the physiological roles mediated by mGlu1 receptors. The synthesis and the structure-activity relationship of this new class of positive allosteric modulators of mGlu1 receptors will be discussed in detail.

A generalized synthesis of 3-amino-5-aryl-, 3-amino-5-polyfluorophenyl-, and 3-amino-5-alkyl-1,2,4-oxadiazoles through ring-degenerate rearrangements

A generalized synthesis of 3-amino-5-aryl-, 3-amino-5-polyfluorophenyl- and 3-amino-5-alkyl-1,2,4-oxadiazoles has been developed starting from the 3-amino-5-methyl-1,2,4-oxadiazole as a common synthon. Aroylation or alkanoylation of this aminooxadiazole,

A generalized and efficient synthesis of 3-amino-, 3-(N-alkylamino)-, 3-(N,N-dialkylamino)-5-alkyl-1,2,4-oxadiazoles by irradiation of 3-alkanoylamino-4-phenyl-1,2,5-oxadiazoles (Furazans)

Irradiation of 3-alkanoylamino-4-phenyl-1,2,5-oxadiazoles (furazans) at λ = 310 nm in methanol and in the presence of ammonia, primary or secondary aliphatic amines produced excellent yields of 3-amino-, 3-(N-alkylamino)-, 3-(N,N-dialkylamino)-5-alkyl-1,2