17116-66-4

Basic information

• Product Name: 2-METHYL-N-(3-NITROPHENYL)ACRYLAMIDE
• Synonyms: 2-METHYL-N-(3-NITROPHENYL)ACRYLAMIDE
• CAS NO: 17116-66-4
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.2
• Mol File: 17116-66-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-METHYL-N-(3-NITROPHENYL)ACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-N-(3-NITROPHENYL)ACRYLAMIDE(17116-66-4)
• EPA Substance Registry System: 2-METHYL-N-(3-NITROPHENYL)ACRYLAMIDE(17116-66-4)

Safety Data

• Hazardous Substances Data: 17116-66-4(Hazardous Substances Data)

Upstream product

• 99-09-2 3-nitro-aniline 
• 920-46-7 Methacryloyl chloride 

Downstream Products

• 1373225-12-7 C₁₁H₁₂N₂O₃ 
• 1613024-28-4 C₁₇H₁₆N₂O₅S 
• 1613024-29-5 1,3-dimethyl-6-nitro-3-((phenylsulfonyl)methyl)indolin-2-one 

Relevant articles and documents

Catalyst-free direct arylsulfonylation of N-arylacrylamides with sulfinic acids: A convenient and efficient route to sulfonated oxindoles

A simple, efficient and catalyst-free procedure has been developed for the construction of sulfonated oxindoles via the direct arylsulfonylation of N-arylacrylamides with sulfinic acids. The present protocol, which simply utilizes cheap oxidants, readily-available starting materials, and catalyst-free conditions, provides an alternative and highly attractive approach to a series of sulfonated oxindoles with high atom efficiency and excellent functional group tolerance. This journal is the Partner Organisations 2014.

Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature

A palladium-catalyzed intramolecular oxidative aryltrifluoromethylation reaction of activated alkenes has been explored. The reaction allows for an efficient synthesis of a variety of CF3-containing oxindoles. Preliminary mechanistic study indicated that the reaction involves a Csp 3-PdIV(CF3) intermediate, which undergoes reductive elimination to afford a Csp3-CF3 bond.