Reaction of ortho-lithiated protected anilines with o-hydroxycarbonyl compounds: formation of quino- and pyranoquino-acridines
Reaction of N-tert-butoxycarbonyl-2-lithioaniline and p-anisidine with 1-hydroxy-3-methoxy-10-methylacridone and noracronycine gave quinoacridines and pyranoquinoacridines respectively, which are related to biologically active compounds recently isolated from various marine animals.