- Method for synthesizing benzoxazole through microwave radiation of benzamide compound in water phase
-
The invention discloses a method for synthesizing benzoxazole through microwave radiation of a benzamide compound in a water phase. The benzamide compound is added into the water phase under the microwave condition to be subjected to a cyclization reaction for generating the benzoxazole under the alkali condition, and the method for preparing the benzoxazole is environmentally friendly, easy and convenient to operate, safe, low in cost and efficient. Compared with the prior art, the method can be applied to a large number of functional groups, the yield is high, the number of by-products is small, and the method is easy to operate, safe, low in cost and environmentally friendly. (Please see the specifications for the formula).
- -
-
Paragraph 0095
(2019/03/08)
-
- Highly efficient Ir-catalyzed asymmetric hydrogenation of benzoxazinones and derivatives with a Br?nsted acid cocatalyst
-
The Ir-catalyzed highly efficient asymmetric hydrogenation of benzoxazinones and derivatives was successfully developed with N-methylated ZhaoPhos L5 as the ligand, which may display a new activation mode with a single anion-binding interaction among the
- Han, Zhengyu,Liu, Gang,Wang, Rui,Dong, Xiu-Qin,Zhang, Xumu
-
p. 4328 - 4333
(2019/04/17)
-
- ANTI-INFECTIVE COMPOUNDS
-
The present invention relates to small molecule compounds having the general formula (I): wherein A is a moiety selected from the group consisting of formulae (A) to (K) and their use in the treatment of bacterial infections, in particular Tuberculosis.
- -
-
Page/Page column 41
(2016/06/28)
-
- BICYCLIC HETEROCYCLE SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS
-
Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a bicyclic heterocycle, and R1, R3, R4, R5 and R6 are as defined herein, that are useful as kinase modulators, including IRAK-4 modulation.
- -
-
Paragraph 00258
(2014/05/24)
-
- Iodine-mediated arylation of benzoxazoles with aldehydes
-
A simple and efficient methodology for the arylation of benzoxazoles with aldehydes using iodine as the mediator has been developed. The reaction proceeded smoothly with a range of substrates to give the corresponding arylated products in moderate to good yields.
- Teo, Yew Chin,Riduan, Siti Nurhanna,Zhang, Yugen
-
supporting information
p. 2365 - 2368
(2013/09/12)
-
