172915-62-7Relevant articles and documents
Selective recognition of HIV RNA by dinuclear metallic ligands
Li, Xuedong,Chen, Bo,Lan, Ling,Wang, Ruili,Luo, Duqiang,Liu, Li,Cheng, Liang
, p. 1637 - 1640 (2018)
We describe the development of dinuclear metallic ligands to target specific HIV RNA structures. Two series of dipyridinyl-N bridged dinuclear metal complexes were synthesized in moderate to good yields and their binding activities toward TAR and RRE RNA were studied both experimentally and theoretically. The docking calculation elucidated some structure features in dimetallic complexes that can affect TAR RNA-binding properties.
A streamlined synthesis for 2,7-diformyl-1,8-naphthalenediol
Glaser, Thorsten,Liratzis, Ioannis
, p. 735 - 737 (2004)
2,7-Diformyl-1,8-naphthalenediol, an extension of the numerously used precursor 2,6-diformylphenol for the synthesis of various ligand systems, has been synthesized by a double Directed ortho Metalation reaction.
Optically Triggered Stepwise Double-Proton Transfer in an Intramolecular Proton Relay: A Case Study of 1,8-Dihydroxy-2-naphthaldehyde
Peng, Chia-Yu,Shen, Jiun-Yi,Chen, Yi-Ting,Wu, Pei-Jhen,Hung, Wen-Yi,Hu, Wei-Ping,Chou, Pi-Tai
, p. 14349 - 14357 (2015)
1,8-Dihydroxy-2-naphthaldehyde (DHNA), having doubly intramolecular hydrogen bonds, was strategically designed and synthesized in an aim to probe a long-standing fundamental issue regarding synchronous versus asynchronous double-proton transfer in the excited state. In cyclohexane, DHNA shows the lowest lying S0 →S1 (π-π) absorption at ～400 nm. Upon excitation, two large Stokes shifted emission bands maximized at 520 and 650 nm are resolved, which are ascribed to the tautomer emission resulting from the first and second proton-transfer products, denoted by TA and TB, respectively. The first proton transfer (DHNA → TA) is ultrafast (-1 and (3.6 ps)-1, respectively. The fast equilibrium leads to identical population lifetimes of ～54 ps for both TA and TB tautomers. Similar excited-state double-proton transfer takes place for DHNA in a single crystal, resulting in TA (560 nm) and TB (650 nm) dual-tautomer emission. A comprehensive 2D plot of reaction potential energy surface further proves that the sequential two-step proton motion is along the minimum energetic pathway firmly supporting the experimental results. Using DHNA as a paradigm, we thus demonstrate unambiguously a stepwise, proton-relay type of intramolecular double-proton transfer reaction in the excited state, which should gain fundamental understanding of the multiple proton transfer reactions.
Neutral Bimetallic Transition Metal Phenoxyiminato Catalysts and Related Polymerization Methods
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Page/Page column 10; 11, (2013/03/26)
A catalyst composition comprising a neutral bimetallic diphenoxydiiminate complex of group 10 metals or Ni, Pd or Pt is disclosed. The compositions can be used for the preparation of homo- and co-polymers of olefinic monomer compounds.
Highly selective visual detection of Cu(II) utilizing intramolecular hydrogen bond-stabilized merocyanine in aqueous buffer solution
Guo, Zhao-Qi,Chen, Wei-Qiang,Duan, Xuan-Ming
supporting information; experimental part, p. 2202 - 2205 (2010/08/06)
A Cu2+-specific colorimetric sensor 1, which is stabilized by an intramolecular hydrogen bonding, was designed and developed. The color of 1 changes from purple to blue on addition of 1.0 μM Cu2+ in aqueous buffer solution, which can be detected by the naked eye. The analytical detection limit for Cu2+ by the naked eye is as low as 1.0 μM. The stoichiometry for 1 and Cu2+ in complex is 2:1 in aqueous solution.
Bimetallic effects for enhanced polar comonomer enchainment selectivity in catalytic ethylene polymerization
Rodriguez, Brandon A.,Delferro, Massimiliano,Marks, Tobin J.
supporting information; scheme or table, p. 5902 - 5919 (2009/09/25)
The synthesis and characterization of the bimetallic 2,7-di-[(2,6- diisopropylphenyl)imino]-1,8- naphthalenediolato group 10 metal polymerization catalysts {[Ni(CH 3)] 2[1,8-(O) 2C 10H 4-2,7-[CH=N(2,6- Pr 2C 6H 3)](PMe 3) 2} and {[Ni(1-naphthyl)] 2[1,8-(O) 2C 10H 4-2,7-[CH=N(2,6-Pr 2C 6H 3)](PPh 3) 2} [FI 2-Ni 2(PR 3) 2] are presented, along with the synthesis and characterization of the mononuclear analogues {Ni(CH 3)[3- tBu- 2-(0)C 6H 3CH=N(2,6- iPr 2C 6H 3)](PMe) 3}and{Ni(1-naphthyl)[3- tBu-2-(0)C 6H 3CH=N(2,6- iPr 2C 6H 3)](PPh) 3}[FI- Ni (PR 3)].Monometallic Ni catalysts were also prepared by functionalizing one lig ation center of the bimetallic ligand with a trimethylsilyl group (TMS),yielding {Ni(CH 3)[1,8-(O)(TMSO)C 10H 4-2,7-[CH=N(2,6- iPr 2C 6H 3)](PMe 3)} [TMS-FI 2-Ni(PMe 3)]. The Fl2-Ni 2 catalysts exhibit significant increases in ethylene homopolymerization activity versus the monometallic analogues, as well as increased branching and methyl branch selectivity, even in t he absence of a Ni(cod) 2 cocatalyst. Increasing ethylene concentrations significantly suppress branching and alter branch morphology. FI 2-Ni 2-mediated copolymerizations with ethylene + polar-functionalized norbornenes exhibit a 4-fold increase in comonomer incorporation versus Fl-Ni, yielding copolymers with up to 10percent norbornene copolymer incorporation. FI 2-Ni 2-catalyzed copolymerizations with ethylene + methylacrylate or methyl methacrylate incorporate up to 11percent acrylate comonomer, while the corresponding mononuclear Fl-Ni catalysts incorporate negligible amounts. Furthermore, the FI 2-Ni 2-mediated polymerizations exhibit appreciable polar solvent tolerance, turning over in the presence of ethyl ether, acetone, and even water. The mechanism by which the present cooperative effects take place is investigated, as is the nature of the copolymer microstructures produced.
