17331-91-8 Usage
Uses
Used in Pharmaceutical Research:
Z-TYR-LEU-NH2 is used as a model compound for studying the interactions of peptides with biological systems, which is crucial for understanding their behavior and potential therapeutic effects.
Used in Drug Development:
Z-TYR-LEU-NH2 is utilized as a template in the development of peptide-based drugs, providing insights into the structural requirements for biological activity.
Used in Neurotransmitter Modulation Research:
Z-TYR-LEU-NH2 is used as a research tool to explore its potential role in modulating neurotransmitter activity, which could have implications for the treatment of neurological disorders.
Used in Therapeutic Agent Development for Neurological Disorders:
Z-TYR-LEU-NH2 is considered as a potential therapeutic agent for conditions such as neurological disorders, given its effects on neurotransmitter activity.
Used in Therapeutic Agent Development for Chronic Pain:
Z-TYR-LEU-NH2 is also being studied for its potential as a therapeutic agent for chronic pain, suggesting that it may have analgesic properties.
Used in Structure-Activity Relationship Studies:
Z-TYR-LEU-NH2 is used in research to determine the relationship between the chemical structure of peptides and their biological activities, which is vital for the design of effective peptide-based drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 17331-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,3 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 17331-91:
(7*1)+(6*7)+(5*3)+(4*3)+(3*1)+(2*9)+(1*1)=98
98 % 10 = 8
So 17331-91-8 is a valid CAS Registry Number.
17331-91-8Relevant articles and documents
Studies on Enzymatic Peptide Synthesis in Biphasic Aqueous-Organic Systems with Product Extraction
Kuhl, Peter,Schaaf, Regina,Jakubke, Hans-Dieter
, p. 1279 - 1288 (1987)
The dipeptide derivatives Z-Tyr-Leu-NH2 and Mca-Tyr-Leu-NH2 were synthesized by α-chymotrypsin-catalyzed coupling reactions in solvent systems consisting of buffer and ethyl acetate.In comparison to a pure aqueous medium, in which only insignificant synth
ENZYME PEPTIDE SYNTHESIS BY AN ITERATIVE PROCEDURE IN A NUCLEOPHILE POOL
Petkov, D. D.,Stoineva, I. B.
, p. 3751 - 3754 (1984)
An effective method for enzyme solubility-controlled synthesis of peptides, consisting in an iterative addition of equivalent amounts of acyl and amine components to a solution(nucleophile pool) containing the enzyme and a large excess of the amine component, is described.
Enzymatic C-terminal amidation of amino acids and peptides
Nuijens, Timo,Piva, Elena,Kruijtzer, John A.W.,Rijkers, Dirk T.S.,Liskamp, Rob M.J.,Quaedflieg, Peter J.L.M.
experimental part, p. 3777 - 3779 (2012/09/22)
Herein, we describe two versatile and high yielding enzymatic approaches for the conversion of semi-protected amino acid and peptidyl C-terminal α-carboxylic acids into their corresponding amides. In the first approach, the lipase Candida antarctica lipase-B (Cal-B), and in the second approach, the protease Subtilisin A, are used, respectively. We found that by using the ammonium salt of the α-carboxylic acid instead of separate ammonia sources, the enzymatic amidation reactions proceeded much faster without side reactions and gave near to quantitative yields of products.
