173352-21-1

Basic information

• Product Name: CM 346
• Synonyms: CM 346;Obenoxazine;Afobazole;CM 346(Obenoxazine);CM 346 4-(2-(5-ETHOXY-1H-BENZO[D]IMIDAZOL-2-YLTHIO)ETHYL)MORPHOLINE;Obenoxazine HCl;Obenoxazine hydrochloride;Fabomotizole
• CAS NO: 173352-21-1
• Molecular Formula: C15H21N3O2S
• Molecular Weight: 307.41114
• Product Categories: Inhibitors
• Mol File: 173352-21-1.mol

Chemical Properties

• Boiling Point: 504.8±60.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• PKA: 10.04±0.10(Predicted)
• CAS DataBase Reference: CM 346(CAS DataBase Reference)
• NIST Chemistry Reference: CM 346(173352-21-1)
• EPA Substance Registry System: CM 346(173352-21-1)

Safety Data

• Hazardous Substances Data: 173352-21-1(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
CM 346 is used as a herbicide for controlling broadleaf weeds and invasive plants in agricultural settings, ensuring the healthy growth of crops and reducing competition for resources.
Used in Forestry Industry:
CM 346 is used as a vegetation management tool in forestry, helping to control unwanted vegetation and promote the growth of desired tree species.
Used in Residential Settings:
CM 346 is used for maintaining landscapes and lawns in residential areas by eliminating unwanted broadleaf weeds, enhancing the aesthetic appeal of the surroundings.
Used in Pastures and Rangeland:
CM 346 is used as a herbicide in pastures and rangeland to control a wide range of broadleaf weeds, improving the quality of forage for livestock and supporting sustainable grazing practices.
Used in Non-Crop Areas:
CM 346 is used for managing vegetation in non-crop areas, such as roadsides, railways, and industrial sites, to prevent the overgrowth of unwanted plants and maintain a clean and safe environment.
It is crucial to use CM 346 with caution and in compliance with local regulations to minimize any potential negative impacts on the environment and non-target species.

Upstream product

• 3647-69-6 4-(2-chloroethyl)morpholine hydrochride 
• 55489-15-1 2-mercapto-5-ethoxybenzimidazole 

Relevant articles and documents

The giardicidal activity of lobendazole, fabomotizole, tenatoprazole and ipriflavone: A ligand-based virtual screening and in vitro study

A ligand-based virtual screening study to search for giardicidal compounds on a 6551 ChEMBL drugs database was carried out using molecular similarity. Three fingerprints implemented in MayaChemTools with different design and validated by ROC curves, were used. Twelve compounds were retrieved from this screening, from which, four representative compounds were selected to carry out biological assays. Whereas two compounds were commercially available, the additional two compounds were synthesized during the development of this work. The biological assays revealed that the compounds possess in vitro activity against five strains of Giardia intestinalis, each with different susceptibility/resistance rates to metronidazole, albendazole and nitazoxanide. Particularly, tenatoprazole showed the best effect against the WB and IMSS strains. Furthermore, fabomotizole, tenatoprazole and ipriflavone showed a higher activity against resistant strains than the reference drugs: metronidazole, albendazole and nitazoxanide.

2-mercaptobenzimidazole derivatives possessing pharmacological activity

2-mercaptobenzimidazole derivatives of the general formula wherein: N=0,2,3; R-hydrogen atom, aralkyls; R1-lower alkyls, alkenyls, dialkylamino, a saturated amine monocyclic residue which may contain an additional heteroatom; R2and R3/sup