The Synthesis of N-Substituted Ureas I: The N-Alkylation of Ureas
Urea and N-alkylureas are N'-alkylated in low yields using aprotic dipolar solvents, like dimethylsulfoxide, solid potassium hydroxide, and alkyl halides.Phase transfer catalysis with tetrabutylammonium chloride in refluxing toluene results in high yield
Hackl, Kurt A.,Falk, Heinz
p. 599 - 606
(2007/10/02)
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