Convergent syntheses of 3,6-dihydroxydec-4-enolides
The total syntheses of the 3,6-dihydroxydecanolide from Cordyceps militaris and the novel C-3 epimer are reported using a diastereoselective Nozaki-Hiyama-Kishi reaction in the key cyclization to generate the 6R stereocenter.
Killen, Jonathan C.,Axford, Lorraine C.,Newberry, Sarah E.,Simpson, Thomas J.,Willis, Christine L.
supporting information; experimental part
p. 4194 - 4197
(2012/10/08)
The efficient resolution of protected diols and hydroxy aldehydes by lipases: Steric auxilliary approach and synthetic applications
1,n-Diols (n = 2-5) and 2-hydroxy aldehydes protected with a steric auxilliary are transformed by Pseudomonas lipases with high enantioselectivity, thus allowing the efficient resolution of these molecules and the synthesis of related derivatives with high optical purity.
Kim,Lim,Choi,Whang,Ku,Choi
p. 71 - 76
(2007/10/03)
More Articles about upstream products of 174500-52-8