174533-98-3Relevant articles and documents
Characterization, luminescent and magnetic analysis of five new lanthanide complexes based on carboxylate ligands
Xie, Fei,Wang, Lu-Lu,Yang, Ru-Xia,Yu, Yu-Ming,Wang, Duo-Zhi,Zhang, Ya-Xin
, p. 598 - 615 (2021)
Five new lanthanide complexes, [Pr(HL1)(H2O)4]Cl2·2H2O (1), [Ho(HL1) (H2O)3]Cl2·2H2O (2), [Dy(HL1)(H2O)3]Cl2·2H2O (3), [Dy(H2L2)2(H2O)6]Cl3 (4) and [Ce(H2L3)(CH3CO2)2(H2O)2]·H2O (5), based on carboxylate ligands have been prepared. All complexes have been characterized via elemental analysis, single-crystal X-ray diffraction, powder X-ray diffraction and thermogravimetric analysis. According to single-crystal X-ray analysis, 1–3 and 5 are coordination polymers (CPs) with 1D zigzag chains, while 4 is a 0D structure. The 3D supramolecular structures of 1–4 are formed by the interaction of C/N ? H···Cl hydrogen bonds and π···π stacking interactions. In addition, the luminescent and magnetic properties of 1–5 have been discussed.
Design, synthesis, molecular modeling, DFT, ADME and biological evaluation studies of some new 1,3,4-oxadiazole linked benzimidazoles as anticancer agents and aromatase inhibitors
Ahmad, Iqrar,Celik, Ismail,Patel, Harun,?zkay, Yusuf,Acar ?evik, Ulviye,I??k, Ay?en,Kaplanc?kl?, Zafer As?m
, (2022/01/20)
Breast cancer is the most frequent female cancer and second cause of cancer-related deaths among women around the world. Two thirds of breast cancer patients have hormone-dependent tumors, which is very likely be treated with hormonal therapy. Aromatase i
SYNTHESIS OF 2-(SUBSTITUTEDPHENYL)-5-(SUBSTITUTEDHETEROARYL)- 1H-BENZIMIDAZOLE DERIVATIVES AND INVESTIGATION OF THEIR BIOLOGICAL EFFECTS
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Page/Page column 11, (2021/06/26)
The invention is related to the synthesis of 2-((5-(2-(4-Substitutedphenyl)-1H-benzo[d]imidazole-6-yl)-1,3,4-oxadiazole-2-yl)thio)-1-(4substitutedpiperazine-1-yl)-ethane-1-one derivative compounds and investigation of their biological effects. Cytotoxicity of the obtained compounds on 5 different cancer cell lines was evaluated and their selectivity indices were calculated.
Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison
Acar ?evik, Ulviye,Atl? Eklio?lu, ?zlem,Atl?d, ?zlem,Kaplanc?kl?, Zafer As?m,Karaduman, Abdullah Burak,Kaya ?avu?o?lu, Betül,Levent, Serkan,Osmaniye, Derya,Sa?l?k, Begüm Nurpelin
, p. 1657 - 1673 (2020/08/21)
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, 1H-NMR,