Synthesis and QSAR studies on hypotensive 1- (arylpiperazin-1-yl)- 1-oxo-2-(thioaryloxy/aryloxy)propanes
1 -(Arylpiperazin-1-yl)-1-oxo-2- (thioaryloxy/aryloxy)propanes (14-39) have been synthesized and evaluated for hypotensive activity. QSAR studies of these compounds indicate that resonance or electronic parameters for the substituents in the thioaryloxy/a