175278-02-1 Usage
Uses
Used in Pharmaceutical Industry:
ETHYL 3-[3,5-DI(TRIFLUOROMETHYL)PHENYL]-3-OXOPROPANOATE is used as a chemical intermediate for the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical sector, ETHYL 3-[3,5-DI(TRIFLUOROMETHYL)PHENYL]-3-OXOPROPANOATE is utilized as an intermediate in the production of agrochemicals, contributing to the development of effective crop protection agents and other agricultural products.
Used in Flavor and Fragrance Industry:
ETHYL 3-[3,5-DI(TRIFLUOROMETHYL)PHENYL]-3-OXOPROPANOATE is used as a component in the manufacturing of flavors and fragrances, enhancing the sensory experience of various consumer products.
Safety Precautions:
It is important to handle ETHYL 3-[3,5-DI(TRIFLUOROMETHYL)PHENYL]-3-OXOPROPANOATE with care due to its potential hazards. It may be harmful if ingested or inhaled and can cause irritation to the skin and eyes, necessitating proper safety measures during its use and storage.
Check Digit Verification of cas no
The CAS Registry Mumber 175278-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,7 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 175278-02:
(8*1)+(7*7)+(6*5)+(5*2)+(4*7)+(3*8)+(2*0)+(1*2)=151
151 % 10 = 1
So 175278-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H10F6O3/c1-2-22-11(21)6-10(20)7-3-8(12(14,15)16)5-9(4-7)13(17,18)19/h3-5H,2,6H2,1H3
175278-02-1Relevant articles and documents
Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of Racemic β’-Keto-β-Amino Esters via Dynamic Kinetic Resolution
He, Jiayin,Huang, An,Ling, Fei,Wang, Shiliang,Wang, Yifan,Wang, Ze,Zhao, Xianghua,Zhong, Weihui
supporting information, p. 4714 - 4719 (2021/09/02)
An iridium/f-diaphos catalytic system for the enantioselective hydrogenation of α-substituted β-ketoesters via dynamic kinetic resolution is reported. The desired anti β’-hydroxy-β-amino esters were obtained in moderate to good yields (60–95%) with 72–99% ees and 91:9 to 99:1 drs. This protocol tolerates various functional groups and could be easily conducted on gram scale with lower catalyst loading (TON up to 9100). (Figure presented.).
One pot direct synthesis of β-ketoesters via carbonylation of aryl halides using cobalt carbonyl
Baburajan, Poongavanam,Elango, Kuppanagounder P.
supporting information, p. 3525 - 3528 (2014/06/10)
A direct method for the synthesis of β-ketoesters from aryl halides (iodide, bromide) has been described by using cobalt carbonyl as carbon monoxide source in microwave irradiation. Using this protocol, a wide variety of substituted aryl halides has been successfully converted to corresponding β-ketoesters.
