175278-30-5

Basic information

• Product Name: 4-BROMO-2-ETHYLIODOBENZENE
• Synonyms: 4-BROMO-2-ETHYL-1-IODOBENZENE;4-BROMO-2-ETHYLIODOBENZENE;4-BROMO-2-ETHYL-1-IODOBENZENE,97%;4-BroMo-2-ethyl-1-iodobenzene, 97%, stab. with copper;Benzene, 4-broMo-2-ethyl-1-iodo-;4-Bromo-2-ethyl-1-iodobenzene, 97%, stabilized;5-Bromo-2-iodo-1-ethylbenzene;4-Bromo-2-ethyl-1-iodobenzene, stabilized with copper
• CAS NO: 175278-30-5
• Molecular Formula: C₈H₈BrI
• Molecular Weight: 310.96
• Product Categories: Bromine Compounds;Iodine Compounds
• Mol File: 175278-30-5.mol

Chemical Properties

• Boiling Point: 84-86°C 0,4mm
• Flash Point: 84-86°C/0.4mm
• Appearance: liquid
• Density: 1.937 g/cm³
• Vapor Pressure: 0.00513mmHg at 25°C
• Refractive Index: 1.62
• Storage Temp.: Sealed in dry,Room Temperature
• Sensitive: Light Sensitive
• CAS DataBase Reference: 4-BROMO-2-ETHYLIODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-ETHYLIODOBENZENE(175278-30-5)
• EPA Substance Registry System: 4-BROMO-2-ETHYLIODOBENZENE(175278-30-5)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 175278-30-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-Bromo-2-ethyl iodobenzene is used as a key intermediate in the synthesis of a range of chemical products. Its halogenated nature allows it to participate in coupling reactions, making it a valuable component in the production of biologically or chemically significant molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Bromo-2-ethyl iodobenzene is used as a building block for the synthesis of various drug molecules. Its reactivity in coupling reactions enables the creation of new compounds with potential therapeutic applications.
Used in Chemical Research:
4-Bromo-2-ethyl iodobenzene is also utilized in chemical research as a model compound for studying the properties and reactions of halogenated aromatic compounds. This helps in understanding the fundamental principles of organic chemistry and contributes to the development of new synthetic methods and strategies.
Safety Considerations:
When handling 4-Bromo-2-ethyl iodobenzene, it is essential to follow safety protocols, as it can cause eye and skin irritations. Proper protective measures, such as wearing gloves and safety goggles, should be taken to minimize the risk of exposure.

InChI:InChI=1/C8H8BrI/c1-2-6-5-7(9)3-4-8(6)10/h3-5H,2H2,1H3

Upstream product

• 45762-41-2 4-bromo-2-ethylaniline 

Downstream Products

• 1046861-62-4 4-bromo-2-ethylphenylboronic acid 
• 1160561-22-7 4-bromo-2,6-diethylphenylboronic acid 
• 1114808-89-7 4-bromo-2-ethylbenzaldehyde 
• 1237529-61-1 (4-bromo-2-ethyl-phenyl)(furan-2-yl)methanol 
• 1112412-95-9 (5-bromo-2-ethylphenyl)furan-2-ylmethanol 
• 1360066-70-1 8-((4-bromo-2-ethylphenyl)thio)-9H-purin-6-amine 
• 943741-74-0 [3-[(tert-butoxycarbonyl-methyl-amino)-methyl]-4-(propane-2-sulfonyl)-phenyl]-carbamic acid 2-(4-bromo-2-ethyl-phenyl)-ethyl ester 
• 943741-75-1 4-(2-(3-((tert-butoxycarbonyl(methyl)amino)methyl)-4-(isopropylsulfonyl)phenylcarbamoyloxy)ethyl)-3-ethylphenylboronic acid 
• 943741-46-6 2-(4-bromo-2-ethylphenyl)ethanol 
• 943741-44-4 4-bromo-2-ethyl-1-vinylbenzene 

Relevant articles and documents

Discovery of 5-(2-chloro-4′-(1H-imidazol-1-yl)-[1,1′-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD

Endogenous nitrosothiols (SNOs) including S-nitrosoglutathione (GSNO) serve as reservoir for bioavailable nitric oxide (NO) and mediate NO-based signaling, inflammatory status and smooth muscle function in the lung. GSNOR inhibition increases pulmonary GS

IMIDAZOLE BIARYL COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS

The present disclosure is directed to compounds of formula (Ie) and pharmaceutically acceptable salts thereof, wherein A, B, R1, R2, m, n, X1, X2, X3 and X4 are as defined herein, which are active as inhibitors of S-Nitrosoglutathione reductase (GSNOR). These compounds prevent, inhibit, or suppress the action of GSNOR and are therefore useful in the treatment of GSNOR mediated diseases, disorders, syndromes or conditions such as, e.g., pulmonary hypertension, acute respiratory distress syndrome (ARDS), asthma, bronchospasm, cough, pneumonia, pulmonary fibrosis, interstitial lung diseases, cystic fibrosis and chronic obstructive pulmonary disease (COPD).

4-PHENYLPYRANE-3,5-DIONES, 4-PHENYLTHIOPYRANE-3,5-DIONES AND 2-PHENYLCYCLOHEXANE-1,3,5-TRIONES AS HERBICIDES

Pyrandione, thiopyrandione and cyclohexanetrione compounds, which are suitable for use as herbicides.