175610-95-4Relevant articles and documents
Microbial hydroxylation of 2-cycloalkylbenzoxazoles. Part I. Product spectrum obtained from Cunninghamella blakesleeana DSM 1906 and Bacillus megaterium DSM 32
De Raadt,Griengl,Petsch,Plachota,Schoo,Weber,Braunegg,Kopper,Kreiner,Zeiser,Kieslich
, p. 467 - 472 (1996)
2-Cycloalkyl-1,3-benzoxazoles and -thiazoles (ring sizes C-3 to C-8) were biotransformed using the title microorganisms. Products of preparative importance were (1S,3S)-3-(benz-1,3-oxazol-2-yl)cyclopentan-1-ol 6, (1R)-3-(benz-1,3-oxazol-2-yl)cyclopentan-1-one 8, (1R,2R)-2-(benz-1,3-oxazol-2-yl)cyclohexan-1-ol 14 and the corresponding cycloheptanol and cycloheptanone derivatives.
Microbial hydroxylation of 2-cycloalkylbenzoxazoles. Part II. Determination of product structures and enhancement of enantiomeric excess
De Raadt,Griengl,Petsch,Plachota,Schoo,Weber,Braunegg,Kopper,Kreiner,Zeiser
, p. 473 - 490 (2007/10/03)
The determinations of product structures obtained in the microbial hydroxylations of various 2-cycloalkyl-1,3-benzoxazoles using Cunninghamella blakesleeana DSM 1906 and Bacillus megaterium DSM 32 are described. The initially low e.e of 3-(benz-1,3-oxazol