17570-08-0

Basic information

• Product Name: D-Thiaproline
• CAS NO: 17570-08-0
• Molecular Formula: C₅H₈O₂S
• Molecular Weight: 133.16
• Mol File: 17570-08-0.mol

Chemical Properties

• CAS DataBase Reference: D-Thiaproline(CAS DataBase Reference)
• NIST Chemistry Reference: D-Thiaproline(17570-08-0)
• EPA Substance Registry System: D-Thiaproline(17570-08-0)

Safety Data

• Hazardous Substances Data: 17570-08-0(Hazardous Substances Data)

Upstream product

• 26551-57-5 ethyl [(3-chloropropyl)thio]acetate 
• 865-47-4 potassium tert-butylate 

Relevant articles and documents

Early Development Scale-Up of a Novel CXCR Antagonist: Focus on Racemic and Stereoselective Routes of a Key Intermediate

Efforts toward a convenient and scalable process for the synthesis of a novel CXCR antagonist 1 are described, with a specific focus on a chiral key intermediate. Two generations of a racemic route have been developed for short-term deliveries, and a ster

Process for the preparation of optically active carboxylic acids and amide intermediates

The present invention provides a process for the preparation of optically active carboxylic acids of the formula I* or II* STR1 in which X is an oxygen or sulfur atom and n is 1 or 2. The process comprises reacting a racemic carboxylic acid I or II or its derivatives with an optically active 2-amino-carboxylic acid ester to give the diastereomeric carboxylic acid amides, separating the diastereomers and, after cleavage of the amide bond, isolating the optically active carboxylic acids of the general formula I* or II*. The invention also provides certain novel optically active carboxylic acid amides and a tetrahydrothiopyran-2-carboxylic acid.