Trialkylalanes in palladium-catalyzed chemo- and regioselective alkylations
Carbosubstitution in halogenoazines with alkyl groups is readily effected under the influence of Pd-catalysis with alanes as the donor of the alkyl group.
RAS modulating compounds and methods of using the same are provided. The compounds find use in modulating the activity of a target RAS in a sample. The target RAS can be a mutant RAS that is implicated in a disease of interest. In some cases, the subject
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CHEMICAL ENTITIES AND THERAPEUTIC USES THEREOF
Certain chemical entities that modulate PI3 kinase activity, and chemical entities, pharmaceutical compositions, and methods of treatments of diseases and conditions associated with PB kinase activity are described.
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Trialkylalanes in palladium-catalyzed C-alkylations of azines
Carbo-substitution with alkyl groups in halogenoazines is readily effected under the influence of Pd-catalysis with alanes as the donor of the alkyl group. Acta Chemica Scandinavica 1997.