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4-Benzyloxy β-Hydroxy TaMoxifen, a hydroxylated analogue of Tamoxifen (T006000), is a white solid with anti-estrogenic and anti-tumor properties. It is a pharmaceutical compound that has been synthesized to enhance the therapeutic effects of Tamoxifen, a well-known drug used in the treatment of breast cancer.

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  • 176671-78-6 Structure
  • Basic information

    1. Product Name: 4-Benzyloxy β-Hydroxy TaMoxifen
    2. Synonyms: 4-Benzyloxy β-Hydroxy TaMoxifen;(Z)-γ-[[4-[2-(diMethylaMino)ethoxy]phenyl][4-(phenylMethoxy)phenyl]Methylene]-benzenepropanol;4-Benzyloxy 2-Hydroxy Tamoxifen
    3. CAS NO:176671-78-6
    4. Molecular Formula: C33H35NO3
    5. Molecular Weight: 493.6359
    6. EINECS: N/A
    7. Product Categories: Aromatics;Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Drug Analogues, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 176671-78-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-Benzyloxy β-Hydroxy TaMoxifen(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-Benzyloxy β-Hydroxy TaMoxifen(176671-78-6)
    11. EPA Substance Registry System: 4-Benzyloxy β-Hydroxy TaMoxifen(176671-78-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 176671-78-6(Hazardous Substances Data)

176671-78-6 Usage

Uses

Used in Pharmaceutical Industry:
4-Benzyloxy β-Hydroxy TaMoxifen is used as an anti-cancer agent for its anti-estrogenic and anti-tumor properties. It is particularly effective in the treatment of breast cancer, where it can help to inhibit the growth and progression of estrogen receptor-positive tumors.
Used in Research and Development:
In the field of research and development, 4-Benzyloxy β-Hydroxy TaMoxifen serves as a valuable tool for studying the mechanisms of action of Tamoxifen and other related compounds. It can be used to investigate the effects of anti-estrogenic agents on various types of cancer cells and to develop new strategies for cancer treatment.
Used in Drug Delivery Systems:
Similar to Gallotannin, 4-Benzyloxy β-Hydroxy TaMoxifen can also be incorporated into novel drug delivery systems to enhance its bioavailability and therapeutic outcomes. These systems may include organic and metallic nanoparticles, liposomes, or other advanced drug carriers, which can help to improve the delivery of the compound to cancer cells and reduce potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 176671-78-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,6,7 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 176671-78:
(8*1)+(7*7)+(6*6)+(5*6)+(4*7)+(3*1)+(2*7)+(1*8)=176
176 % 10 = 6
So 176671-78-6 is a valid CAS Registry Number.

176671-78-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Benzyloxy β-Hydroxy Tamoxifen

1.2 Other means of identification

Product number -
Other names (Z)-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3-phenyl-4-(4-phenylmethoxyphenyl)but-3-en-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:176671-78-6 SDS

176671-78-6Upstream product

176671-78-6Downstream Products

176671-78-6Relevant articles and documents

Tri-phenyl alkene derivatives and their preparation and use

-

, (2008/06/13)

The invention provides novel compounds of the formula: STR1 wherein R1 and R2, which can be the same or different are H or OH, R3 is STR2 wherein R4 and R5, which can be the same or different are H or

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