176787-96-5 Usage
Uses
Used in Pharmaceutical Industry:
5'-bromo-[2,2'-bithiophene]-5-carbonitrile is used as a reagent for the synthesis of dicationic phenyl-2,2''-bichalcophenes and analogs, which are known for their antiprotozoal properties. These synthesized compounds can be utilized in the development of new drugs to combat protozoan infections, such as malaria, leishmaniasis, and trypanosomiasis.
In the context of the provided materials, 5'-bromo-[2,2'-bithiophene]-5-carbonitrile serves as a crucial intermediate in the synthesis of antiprotozoal agents, contributing to the development of novel treatments for various protozoan diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 176787-96-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,7,8 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 176787-96:
(8*1)+(7*7)+(6*6)+(5*7)+(4*8)+(3*7)+(2*9)+(1*6)=205
205 % 10 = 5
So 176787-96-5 is a valid CAS Registry Number.
176787-96-5Relevant articles and documents
Dicationic phenyl-2,2′-bichalcophenes and analogues as antiprotozoal agents
Ismail, Mohamed A.,Bialy, Serry A. El,Brun, Reto,Wenzler, Tanja,Nanjunda, Rupesh,Wilson, W. David,Boykin, David W.
scheme or table, p. 978 - 984 (2011/03/18)
A series of phenyl-2,2'-bichalcophene diamidines 1a-h were synthesized from the corresponding dinitriles either via a direct reaction with LiN(TMS) 2, followed by deprotection with ethanolic HCl or through the bis-O-acetoxyamidoxime followed by
An efficient synthesis of 5′-(4-cyanophenyl)-2,2′-bifuran-5- carbonitrile and analogues
Ismail, Mohamed A.
, p. 733 - 737 (2007/10/03)
5′-(4-Cyanophenyl)-2,2‰-bifuran-5-carbonitrile (6a) was prepared by two approaches. The first approach involves four steps, employs Stille coupling conditions utilising 2-tributylstannylfuran and 5-bromofuran-2-carboxaldehyde to furnish 3a in excellent yi
