177158-21-3 Usage
Uses
1. Used in Pharmaceutical Applications:
N-[(3S)-TETRAHYDRO-2-OXO-3-FURANYL]-NONANAMIDE is used as a reagent for the preparation of immunogenic conjugates. These conjugates consist of autoinducer and lysine-containing protein, which are essential components in the development of vaccines. The compound plays a crucial role in enhancing the immune response against Gram-negative bacterial infections.
2. Used in Diagnostic Applications:
In addition to its role in vaccine development, N-[(3S)-TETRAHYDRO-2-OXO-3-FURANYL]-NONANAMIDE is also utilized in raising antibodies. These antibodies are vital for the accurate diagnosis of Gram-negative bacterial infections, allowing for timely and effective treatment.
3. Used in Research and Development:
The compound's unique structure and properties make it an interesting subject for further research and development. Scientists can explore its potential applications in various fields, such as drug discovery, chemical synthesis, and material science.
Check Digit Verification of cas no
The CAS Registry Mumber 177158-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,1,5 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 177158-21:
(8*1)+(7*7)+(6*7)+(5*1)+(4*5)+(3*8)+(2*2)+(1*1)=153
153 % 10 = 3
So 177158-21-3 is a valid CAS Registry Number.
177158-21-3Relevant articles and documents
Synthesis and biological evaluation of novel N-α-haloacylated homoserine lactones as quorum sensing modulators
Syrpas, Michail,Ruysbergh, Ewout,Stevens, Christian V.,De Kimpe, Norbert,Mangelinckx, Sven
, p. 2539 - 2549 (2015/02/19)
Novel N-α-haloacylated homoserine lactones, in which a halogen atom was introduced at the α-position of the carbonyl function of the N - acyl chain, have been studied as quorum sensing (QS) modulators and compared with a library of natural N - acylated homoserine lactones (AHLs). The series of novel analogues consists of α-chloro, α-bromo and α-iodo AHL analogues. Furthermore, the biological QS activity of the synthetic AHL analogues compared to the natural AHLs was evaluated. Halogenated analogues demonstrated a reduced activity in the Escherichia coli JB523 bioassay, with the α-iodo lactones being the less active ones and the α-chloro AHLs the most potent QS agonists. Most of the α-haloacylated analogues did not exhibit a significant reduction when tested in the QS inhibition test. Therefore, these novel analogues could be utilized as chemical probes for QS structure-activity studies.
