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177348-28-6

Di-tert-butyl chloromethylphosphonate is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and antiviral agents.

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  • 177348-28-6 Structure

  • Basic information

    1. Product Name: Di-tert-butyl chloromethylphosphonate
    2. Synonyms: Di-tert-butyl chloromethylphosphonate
    3. CAS NO:177348-28-6
    4. Molecular Formula: C9H20ClO3P
    5. Molecular Weight: 242.680061
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 177348-28-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Di-tert-butyl chloromethylphosphonate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Di-tert-butyl chloromethylphosphonate(177348-28-6)
    11. EPA Substance Registry System: Di-tert-butyl chloromethylphosphonate(177348-28-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 177348-28-6(Hazardous Substances Data)

177348-28-6 Usage

Uses

Used in Pharmaceutical Industry:
Di-tert-butyl chloromethylphosphonate is used as a chemical intermediate for the synthesis of Fostemsavir (864953-29-7), an antiviral agent that targets the hepatitis B virus. Its role in the synthesis process is crucial for the development of effective treatments against viral infections.
Used in Antiviral Research:
Di-tert-butyl chloromethylphosphonate is utilized in the development of novel water-soluble prodrugs of Buparvaquone (B689555), a broad-spectrum antiparasitic agent. The synthesis of these prodrugs aims to improve the solubility and bioavailability of Buparvaquone, enhancing its therapeutic potential in treating various parasitic infections.

Check Digit Verification of cas no

The CAS Registry Mumber 177348-28-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,3,4 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 177348-28:
(8*1)+(7*7)+(6*7)+(5*3)+(4*4)+(3*8)+(2*2)+(1*8)=166
166 % 10 = 6
So 177348-28-6 is a valid CAS Registry Number.

177348-28-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[chloromethyl-[(2-methylpropan-2-yl)oxy]phosphoryl]oxy-2-methylpropane

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:177348-28-6 SDS

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