177493-79-7Relevant articles and documents
Enantioselective organocatalytic singly occupied molecular orbital activation: The enantioselective α-enolation of aldehydes
Jang, Hye-Young,Hong, Jun-Bae,MacMillan, David W. C.
, p. 7004 - 7005 (2007)
The first enantioselective organocatalytic ∞-enolation of aldehydes has been accomplished using singly occupied molecular orbital (SOMO) catalysis. Chiral secondary amines react with aldehydes to form transient enamines that undergo selective one-electron
Mn(III)-based oxidative free radical cyclizations of unsaturated 2-cyclohexenones and aldehydes
Snider, Barry B.,Kiselgof, Eugenia Y.
, p. 6073 - 6084 (2007/10/03)
Oxidative free-radical cyclizations of unsaturated 2-cyclohexenones 9a, 9b, 17, and 24 with Mn(OAc)3 afford unsaturated α'-keto radicals such as 10 that cyclize to afford bicyclic products. The major process with 2-cyclohexenone 27 is conjugate addition of acetate to form β-acetoxy α-keto radical 37. Unsaturated aldehydes 45,57a, and 57b are oxidized to radicals that cyclize to give cyclopentane- and cyclohexanecarboxaldehydes.