Pyrrolobenzothiazepinones and pyrrolobenzoxazepinones: Novel and specific non-nucleoside HIV-1 reverse transcriptase inhibitors with antiviral activity
Two novel classes of pyrrolobenzothiazepinones and pyrrolobenzoxazepinones were investigated as potential anti-AIDS drugs. These compounds were found to inhibit HIV-1 reverse transcriptase (RT) enzyme in vitro and to prevent HIV-1 cytopathogenicity in T4
Campiani, Giuseppe,Nacci, Vito,Fiorini, Isabella,De Filippis, Maria P.,Garofalo, Antonio,Greco, Giovanni,Novellino, Ettore,Altamura, Sergio,Di Renzo, Laura
p. 2672 - 2680
(2007/10/03)
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