- A new route for the convenient synthesis of imidazo[2,1-b]-1,3,4-oxadiazoles and their fungitoxicity
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5-Aryl-1-arylideneamino-1,3,4-oxadiazoles (4a-f) react with trichloroacetic acid with the evolution of carbon dioxide to furnish 5-aryl-2-[(1-aryl-2,2,2-trichloroethyl)amino]-1,3,4-oxadiazoles (6a-f), which undergo ring closure with primary arylamines to
- Yadav,Saigal, Sandhya,Shukla, Supriya
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p. 385 - 387
(2007/10/03)
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- A Facile Synthesis of New Fungitoxic Peptidyl Imidazo-1,3,4-oxadiazoles
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The reaction of 5-aryl-2-arylideneamino-1,3,4-oxadiazoles (5a-d) with trichloroacetic acid followed by ring closure of the isolable intermediates, 5-aryl-2--1,3,4-oxadiazoles (6a-d), with dipeptides (gly.gly and L-ala.gly) yields new 2,6-diaryl-5-peptidyl (gly.gly and L-ala.gly)imino-5,6-dihydroimidazo--1,3,4-oxadiazoles.Two of the compounds (8d and 8h) displayed the in vitro fungitoxicity equivalent to that of a commercial fungicide Mancozeb against A. solani and F. oxysporum at 1000 ppm concentration. - Key words: 1,3,4-oxadiazoles/imidazoles/imidazo-oxadiazoles; petidylimino; the in vitro fungitoxicity
- Yadav, Lal D. S.,Shukla, Supriya,Saigal, Sandhya
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p. 109 - 112
(2007/10/03)
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