A novel asymmetric route to the 1,3-disubstituted tetrahydroisoquinoline, (-)-argemonine
Chiral bicyclic lactam 13 was converted to the natural product (-)-argemonine 9 in six steps. This novel route to argemonine represents a general strategy for the preparation of chiral 1,3-disubstituted tetrahydroisoquinolines.
Munchhof, Michael J.,Meyers
p. 4607 - 4610
(2007/10/03)
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