178421-21-1 Usage
Uses
Used in Pharmaceutical Industry:
Ethyl 6-chloro-5-methylpicolinate is used as a building block for the production of pharmaceuticals due to its potential to contribute to the development of compounds with significant biological activity. Its unique structure allows for the creation of pyridine-based heterocycles, which are of interest in medicinal chemistry for their potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, Ethyl 6-chloro-5-methylpicolinate is utilized as a key starting material for the synthesis of various agrochemicals. Its chemical properties make it suitable for the development of compounds that can be used in crop protection and other agricultural applications, enhancing the industry's ability to create effective and targeted products.
Used in Organic Synthesis:
Ethyl 6-chloro-5-methylpicolinate is also used in organic synthesis as a versatile intermediate. Its reactivity and structural features make it a preferred choice for chemists working on the synthesis of complex organic molecules, including those with potential applications in various fields such as materials science, pharmaceuticals, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 178421-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,4,2 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 178421-21:
(8*1)+(7*7)+(6*8)+(5*4)+(4*2)+(3*1)+(2*2)+(1*1)=141
141 % 10 = 1
So 178421-21-1 is a valid CAS Registry Number.
178421-21-1Relevant articles and documents
A new pathway to substituted 6-chloro-2-pyridinecarboxylic acid derivatives from the reaction of 4,6-dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones with nucleophiles
Dubois, Kristof J.,Hoornaert, Georges J.
, p. 6997 - 7002 (1996)
Reaction of alcohols or amines with 4,6-dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones gives direct conversion into (3,(4,))5-substituted 6-chloro-2-pyridinecarboxylic acid derivatives via selective lactone cleavage followed by rapid elimination of HCl and H2O in the presence of DBU. Copyright
POSITIVE ALLOSTERIC MODULATORS OF MGLUR2
-
, (2011/10/03)
The present invention is directed to 5-substituted 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide and 1,3-dihydro[1,2,5]thiadiazolo[3,4-b]pyridine 2,2,-dioxide derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved
