- Novel [1,2,4]Triazolo[4,3-a]Quinoxaline Derivative, Method For Preparing Same, And Pharmaceutical Composition For Preventing Or Treating BET Protein-Related Diseases, Containing Same As Active Ingredient
-
Provided are a novel [1,2,4]triazolo[4,3-a]quinoxaline derivative, a method for preparing the same, and a pharmaceutical composition for preventing or treating bromodomain extra-terminal (BET) protein-related diseases including cancer and autoimmune disea
- -
-
Paragraph 0976-0979
(2020/02/20)
-
- Novel [1,2,4]triazolo[4,3-a]quinoxaline amino phenyl derivatives or pharmaceutically acceptable salts thereof, preparation method therof and pharmaceutical composition for use in preventing or treating bromodomain extra-terminal(BET) protein activity related diseases containing the same as an active ingredient
-
The present invention refers to [1, 2, 4] triazolo [4, 3 a-a] the [khwi [khwi] roh it was cut aminophenyl derivatives or pharmaceutically acceptable salts, including BET and manufacturing method of active ingredient (bromodomain extra non-terminal) a pharmaceutical composition for preventing or treating protein related disorders are disclosed. The present invention according to [1, 2, 4] triazolo [4, 3 a-a] aminophenyl derivatives of one of the [khwi [khwi] roh it was cut low concentrations in the BET protein family protein and an excellent BRD4 billion number, so that the inducing cytotoxicity against tumor cell lines, BET diseases associated with protein, in particular can be useful in preventing or treating cancer or an autoimmune disease. (by machine translation)
- -
-
Paragraph 0372-0375
(2018/12/12)
-
- Imidazoquinoxaline protein tyrosine kinase inhibitors
-
Novel imidazoquinoxalines and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic disorders.
- -
-
-