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1-(2-Fluorophenyl)-4-oxocyclohexanecarboxylic acid, also known as roxithromycin, is a synthetic derivative of the antibiotic erythromycin. It is a member of the macrolide class of antibiotics, characterized by its ability to inhibit bacterial protein synthesis, thereby preventing the growth and spread of infections. Roxithromycin is recognized for its effectiveness against a broad spectrum of gram-positive and gram-negative bacteria and is generally well-tolerated with a low risk of adverse effects.

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  • 179064-49-4 Structure
  • Basic information

    1. Product Name: 1-(2-Fluorophenyl)-4-oxocyclohexanecarboxylic acid
    2. Synonyms: 1-(2-Fluorophenyl)-4-oxocyclohexanecarboxylic acid
    3. CAS NO:179064-49-4
    4. Molecular Formula: C13H13FO3
    5. Molecular Weight: 236.2389232
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 179064-49-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 410.4±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.297±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 3.70±0.20(Predicted)
    10. CAS DataBase Reference: 1-(2-Fluorophenyl)-4-oxocyclohexanecarboxylic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(2-Fluorophenyl)-4-oxocyclohexanecarboxylic acid(179064-49-4)
    12. EPA Substance Registry System: 1-(2-Fluorophenyl)-4-oxocyclohexanecarboxylic acid(179064-49-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 179064-49-4(Hazardous Substances Data)

179064-49-4 Usage

Uses

Used in Pharmaceutical Industry:
Roxithromycin is utilized as an antibiotic for the treatment of various bacterial infections. Its application is primarily due to its effectiveness in inhibiting protein synthesis in bacteria, which leads to the prevention of infection growth and spread. It is particularly effective against a wide range of gram-positive and gram-negative bacteria.
Used in Respiratory Tract Infections:
In the medical field, roxithromycin is used as a therapeutic agent for respiratory tract infections. Its application in this context is attributed to its ability to target and eliminate bacteria responsible for causing such infections.
Used in Skin and Soft Tissue Infections:
Roxithromycin is also employed as a treatment for skin and soft tissue infections. Its use in this area is due to its effectiveness in combating the bacteria that cause these types of infections and preventing their progression.
Used in Sexually Transmitted Diseases:
Additionally, roxithromycin is used in the treatment of sexually transmitted diseases. Its application in this context is a result of its broad-spectrum antibacterial properties, which make it suitable for targeting the bacteria responsible for various sexually transmitted infections.

Check Digit Verification of cas no

The CAS Registry Mumber 179064-49-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,0,6 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 179064-49:
(8*1)+(7*7)+(6*9)+(5*0)+(4*6)+(3*4)+(2*4)+(1*9)=164
164 % 10 = 4
So 179064-49-4 is a valid CAS Registry Number.

179064-49-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-fluorophenyl)-4-oxocyclohexanecarboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:179064-49-4 SDS

179064-49-4Upstream product

179064-49-4Downstream Products

179064-49-4Relevant articles and documents

Cyclohexane derivatives and their use as therapeutic agents

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Page 41, (2010/02/06)

The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.

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