- REACTION OF 2,4-DISUBSTITUTED CHLOROBENZENES WITH 3-ALKYLAMINO- AND 3-DIALKYLAMINOPROPIONITRILES
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The reaction of 2,4-disubstituted chlorobenzenes with 3-dialkylaminopropionitriles at 65-170 deg C leads to the formation of 2,4-disubstituted N,N-dialkylanilines, and the reaction with 3-alkylaminopropionitriles at 20-130 deg C leads to the formation of 2,4-disubstituted N-alkyl-N-β-cyanoethylanilines.In addition, in the latter case at high temperature (130 deg C) the cyanoethyl group is removed from the substituted N-alkyl-N-β-cyanoethylaniline with the formation of the 2,4-disubstituted N-alkylaniline.
- Plakidin, Val. L.,Vostrova, V. N.
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p. 295 - 303
(2007/10/02)
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