181284-32-2

Basic information

• Product Name: 1H-Pyrrolo[3,2-c]pyridine-2-carboxylicacid,3-amino-,ethylester(9CI)
• Synonyms: 1H-Pyrrolo[3,2-c]pyridine-2-carboxylicacid,3-amino-,ethylester(9CI);ethyl 3-amino-1H-pyrrolo[3,2-c]pyridine-2-carboxylate
• CAS NO: 181284-32-2
• Molecular Formula: C₁₀H₁₁N₃O₂
• Molecular Weight: 205.21
• Product Categories: AMINOACID
• Mol File: 181284-32-2.mol

Chemical Properties

• Boiling Point: 431.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.352±0.06 g/cm3(Predicted)
• PKA: 13.90±0.40(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[3,2-c]pyridine-2-carboxylicacid,3-amino-,ethylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[3,2-c]pyridine-2-carboxylicacid,3-amino-,ethylester(9CI)(181284-32-2)
• EPA Substance Registry System: 1H-Pyrrolo[3,2-c]pyridine-2-carboxylicacid,3-amino-,ethylester(9CI)(181284-32-2)

Safety Data

• Hazardous Substances Data: 181284-32-2(Hazardous Substances Data)

Usage

Molecular Structure

The compound is a pyrrolopyridine derivative, which means it has a core structure that consists of a pyridine ring fused to a pyrrole ring.

Functional Groups

The compound contains a carboxyl group (-COOH) and an amino group (-NH2), which are essential functional groups in organic synthesis and medicinal chemistry.

Ethyl Ester

The compound is an ethyl ester, which means it has an ester functional group (-COO-) derived from ethanol (ethyl alcohol).

Amino Acid Derivative

The compound is an amino acid derivative, as it contains both an amino group and a carboxyl group, which are characteristic of amino acids.

Solubility

The compound's solubility properties may vary depending on the solvent used. However, it is generally more soluble in polar solvents like water, due to the presence of the carboxyl and amino groups.

Reactivity

The compound can undergo various chemical reactions due to the presence of reactive functional groups, such as esterification, amidation, and peptide bond formation.

Applications in Drug Development

The compound has potential applications in drug development and pharmaceutical research, as it can be used as an intermediate in the synthesis of various pharmaceutical compounds.

Biological Interactions

The unique properties of the compound allow it to interact with biological systems, which may contribute to its potential use in medicinal chemistry.

Synthesis

The compound is commonly synthesized as an ethyl ester of 3-amino-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid, which is an important intermediate in the synthesis of other pharmaceutical compounds.

Specific Uses

The specific uses of the compound may vary, but it is generally considered an important intermediate in the synthesis of various pharmaceutical compounds, particularly those with potential therapeutic applications.

Upstream product

• 181284-30-0 ethyl-4-(3-cyanopyridine)glycinate 

Downstream Products

• 1030382-39-8 3-(2-fluoro-4-trimethylsilanyl-phenylamino)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid ethyl ester 
• 1030382-75-2 3-(2-fluoro-4-methylsulfanyl-phenylamino)-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid ethyl ester 

Relevant articles and documents

TRICYCLIC SUBSTITUTED HEXAHYDROBENZ [E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS

The present invention relates to a compound of the formula STR1 and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an α-1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are . alpha.-1 antagonist compositions and a method for antagonizing α-1 receptors and treating BPH.