Synthesis, biological evaluation, and crystallographic studies of extended guanine-based (lin-benzoguanine) inhibitors for tRNA-guanine transglycosylase (TGT)
This paper describes the rational design, synthesis, and biological evaluation of a new generation of inhibitors of the bacterial enzyme tRNA-guanine transglycosylase (TGT), which has been identified as a new target in the fight against bacillary dysenter
Meyer, Emmanuel A.,Donati, Nicola,Guillot, Marine,Schweizer, W. Bernd,Diederich, Francois,Stengl, Bernhard,Brenk, Ruth,Reuter, Klaus,Klebe, Gerhard
p. 573 - 581
(2007/10/03)
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