- Diphenyl methane -4,4’ - diacylhydrazone compound and application thereof
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The invention belongs to the technical field of medicines, and relates to diphenyl methane - 44444, diacylhydrazone series compounds, and application, thereof, and particularly relates to fluorescence quenching, prepared from diphenylmethane - 44444, diacylhydrazone as a raw material DNA and fluorescent responses, at. base pairs, and, shows high in-vitro. antitumor activity DNA of, base pairs, and an application method thereof AT are shown in the field of medical technology, and the method is applied to preparation of antitumor drugs: 520nm and a method; for, inhibiting tumor cell growth is shown 375nm.
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Paragraph 0069-0072
(2020/03/29)
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- Expanding the limit of Pd-catalyzed decarboxylative benzylations
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The Pd-catalyzed decarboxylative cross-coupling of electron-deficient aryl acetates with aryl bromides is reported. The method widens the scope of benzylic partners that can undergo efficient reactivity from highly activated nitrophenylacetates established previously, to a diverse series of substrates bearing modestly stabilizing groups, allowing direct access to functionalized diarylmethanes. Mechanistic studies support the role of dienolates as key intermediates in the coupling process.
- Kong, Duanyang,Moon, Patrick J.,Qian, Wenyu,Lundgren, Rylan J.
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supporting information
p. 6835 - 6838
(2018/06/26)
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- A Convenient Synthesis of MacrocyclicParacyclophanes
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The paracyclophanedienes 9-11 were prepared in good yields by a McMurry cyclization of the bis(4-acylphenyl)methanes 5 and 6 and of bis(4-acetylphenyl) ether (7), respectively. - Key Words: Cyclophanes / Coupling reaction / McMurry reaction
- Gruetzmacher, Hans-Friedrich,Mehdizadeh, Ahmed,Muelverstedt, Astrid
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p. 1163 - 1166
(2007/10/02)
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- New Watersoluble Macrobicyclic Cavities
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The watersoluble macrobicyclic compounds 1, 3, 5a, and 5b have been synthesized for the first time bearing large endolipophilic cavities of different sizes and shapes.They were studied with respect to their interactions towards lipophilic guest compounds.
- Wallon, Alexander,Peter-Katalinic, Jasna,Werner, Ute,Mueller, Walter M.,Voegtle, Fritz
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p. 375 - 379
(2007/10/02)
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