Synthetic studies on the reactions of hydrazine and aroylhydrazide with 5-phneyl-1,3,4-oxadiazol-2-thione
The reaction of 5-phenyl-1,3,4-oxadiazol-2-thione 1 with hydrazine hydrate in refluxing n-butanol afforded benzoylcarbohydrazide 2 which was cyclized to 4-amino-3-chloro-5-phenyl-1,2,4-triazole 3. Compound 3 was used for the synthesis of some new di-or polyheterocyclic derivatives via its reaction with anilines and treating the products with bidentates.
El-Saraf,El-Sayed
p. 3827 - 3839
(2007/10/03)
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