Suzuki cross-coupling of hexachlorobenzene promoted by the Buchwald ligands
The study of cross-coupling between hexachlorobenzene and phenylboronic acid comprised five Buchwald ligands, from which 2-dicyclohexylphosphino-2′-(dimethylamino)biphenyl (DavePHOS) provided the best conversion. When excess of phenylboronic acid was used, a mixture of isomeric tri-, tetra- and pentaphenyl-substituted derivatives in the ~10:70:20 ratio was obtained, along with minor amounts of hydrodechlorination products.
Burukin, A. S.,Vasil’ev, A. A.,Zhdankina, G. M.,Zlotin, S. G.
p. 169 - 172
(2022/02/17)
Bis(tetrazolyl)benzenes as ligands in the Suzuki reaction: Promoters or inhibitors?
The Suzuki cross-coupling with phenylboronic acid in the presence of the Pd(OAc)2/K3PO4/DMF catalytic system was successful for aryl bromides and somewhat poorer for aryl chlorides. Addition of 1,3-bis(tetrazol-1-yl)benzene or its analogs lowered the yields of biaryls.
Burukin,Vasil'ev,Merkulova,Struchkova,Zlotin
p. 118 - 122
(2007/10/03)
Cross-coupling of polychloroarenes with phenylboronic acid and organozinc compounds catalyzed by palladium complexes
Hexachlorobenzene and 1,2,4,5-tetrachlorobenzene react with phenylboronic acid by a C-C cross-coupling mechanism with a Pd(dba)2/P(Bu t)3 system (dba is dibenzylideneacetone) or palladium-azole complexes as catalysts, or with organozinc compounds in the presence of Pd(PPh3)4 to afford substitution products of one or two chlorine atoms in moderate yields.
Burukin,Vasil'ev,Chizhov,Zlotin
p. 970 - 974
(2007/10/03)
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