Analogues of capsaicin with agonist activity as novel analgesic agents: Structure-activity studies. 4. Potent, orally active analgesics
Structural features of three regions of the capsaicin molecule necessary for agonist properties were delineated by a previously reported modular approach. These in vitro agonist effects were shown to correlate with analgesic potency in rodent models. Comb
Wrigglesworth, Roger,Walpole, Christopher S. J.,Bevan, Stuart,Campbell, Elizabeth A.,Dray, Andy,Hughes, Glyn A.,James, Iain,Masdin, Kay J.,Winter, Janet
p. 4942 - 4951
(2007/10/03)
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