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1841078-75-8

3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinoline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1841078-75-8 Structure

  • Basic information

    1. Product Name: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinoline
    2. Synonyms:
    3. CAS NO:1841078-75-8
    4. Molecular Formula:
    5. Molecular Weight: 245.283
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1841078-75-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinoline(1841078-75-8)
    11. EPA Substance Registry System: 3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinoline(1841078-75-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1841078-75-8(Hazardous Substances Data)

1841078-75-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1841078-75-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,4,1,0,7 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1841078-75:
(9*1)+(8*8)+(7*4)+(6*1)+(5*0)+(4*7)+(3*8)+(2*7)+(1*5)=178
178 % 10 = 8
So 1841078-75-8 is a valid CAS Registry Number.

1841078-75-8Downstream Products

1841078-75-8Relevant articles and documents

Discovery of 6-(Fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)

Walji, Abbas M.,Hostetler, Eric D.,Selnick, Harold,Zeng, Zhizhen,Miller, Patricia,Bennacef, Idriss,Salinas, Cristian,Connolly, Brett,Gantert, Liza,Holahan, Marie,O'Malley, Stacey,Purcell, Mona,Riffel, Kerry,Li, Jing,Balsells, Jaume,Obrien, Julie A.,Melquist, Stacey,Soriano, Aileen,Zhang, Xiaoping,Ogawa, Aimie,Xu, Serena,Joshi, Elizabeth,Della Rocca, Joseph,Hess, Fred J.,Schachter, Joel,Hesk, David,Schenk, David,Struyk, Arie,Babaoglu, Kerim,Lohith, Talakad G.,Wang, Yaode,Yang, Kun,Fu, Jianmin,Evelhoch, Jeffrey L.,Coleman, Paul J.

, p. 4778 - 4789 (2016/06/13)

Neurofibrillary tangles (NFTs) made up of aggregated tau protein have been identified as the pathologic hallmark of several neurodegenerative diseases including Alzheimer's disease. In vivo detection of NFTs using PET imaging represents a unique opportuni

PYRROLO[2,3-C]PYRIDINES AS IMAGING AGENTS FOR NEUROFIBRILARY TANGLES

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Page/Page column 46, (2016/01/01)

Pyrrolopyridine compounds of formula (I) or their pharmaceutically acceptable salts are disclosed, which may be suitable for imaging tau aggregates, b-sheet aggregates, beta-amyloid aggregates or alpha- synuclein aggregates, and hence are useful in binding and imaging tau aggregates in Alzheimer's patients. More specifically, the compounds are used as tracers in positron emission tomography (PET) imaging to study tau deposits in brain in vivo to allow diagnosis of Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology. Futher, the compounds are useful for measuring clinical efficacy of therapeutic agents for Alzheimer's disease and other neurodegenerative diseases characterized by tau pathology.

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