18457-46-0 Usage
Uses
Used in Pharmaceutical Industry:
Taxinine J is used as a potential lead compound for the development of new anti-cancer drugs due to its potent cytotoxic activity against various cancer cell lines. Its ability to interfere with microtubule dynamics makes it a valuable asset in the fight against cancer.
Used in Cancer Research:
Taxinine J is utilized as a research tool to study the effects of microtubule dynamics on cell division and the development of cancer. Understanding its mechanism of action can provide insights into the development of novel therapeutic strategies targeting cancer cells.
Used in Drug Synthesis:
Due to its complex and unique chemical structure, Taxinine J presents a challenging target for chemical synthesis. Researchers are interested in developing efficient synthetic routes to produce this compound, which can facilitate its use in drug development and cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 18457-46-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,5 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18457-46:
(7*1)+(6*8)+(5*4)+(4*5)+(3*7)+(2*4)+(1*6)=130
130 % 10 = 0
So 18457-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C37H46O10/c1-20-28-17-27-18-29(43-22(3)38)21(2)33(36(27,7)8)34(45-24(5)40)35(46-25(6)41)37(28,9)31(44-23(4)39)19-30(20)47-32(42)16-15-26-13-11-10-12-14-26/h10-16,27-31,34-35H,1,17-19H2,2-9H3/b16-15+
18457-46-0Relevant articles and documents
New taxanes from the needles of Taxus canadensis
Zhang,Sauriol,Mamer,Zamir, Lolita O.
, p. 929 - 933 (2007/10/03)
Nine minor taxanes were identified for the first time in the Canadian yew needles. Four of these metabolites are new: 5-epi-cinnamoylcanadensene (1), 2,9,10,13-tetraacetoxy-20-cinnamoyloxy-taxa-4(5),11(12)-diene (2), 2'-acetyl-epi-taxol (3), and 9-deacety
