4-Aryl-1-piperazinylalkyl derivatives of 1,2,3,4-tetrahydro-β-carboline ring system. Synthesis and preliminary in vivo studies
Three series of compounds containing a 4-aryl-1-piperazinylalkyl fragment attached to a different position of the indole (A) or 1,2,3,4-tetrahydro-β-carboline (B, C) have been prepared. The quantitative relationship between the structure of some derivatives and their sedative effect was found using the Free-Wilson approach.
Cegla,Boksa,Chojnacka-Wojcik,Misztal
p. 932 - 936
(2007/10/03)
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