- Dabigatran etexilate intermediate synthesis method
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The invention discloses dabigatran etexilate, an intermediate thereof with a formula (5), and a synthesis method of a derivative thereof. According to the synthesis method, a compound represented by a formula (2) is subjected to a compound represented by a formula (4), such that a compound represented by the formula (5) is obtained; the compound represented by the formula (5) is hydrolyzed, and is subjected to a reaction with 3-(pyridin-2-ylamino)ethyl propionate, such that dabigatran etexilate is prepared.
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