185756-31-4

Basic information

• Product Name: Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol
• Synonyms: Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol;2,5-isosorbide bis-4-hydroxybenzoat;(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-hydroxybenzoate)
• CAS NO: 185756-31-4
• Molecular Formula: C₂₀H₁₈O₈
• Molecular Weight: 386.35212
• Mol File: 185756-31-4.mol

Chemical Properties

• Boiling Point: 611.9±55.0 °C(Predicted)
• Appearance: /
• Density: 1.49±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0Pa at 20-50℃
• Storage Temp.: 2-8°C
• PKA: 7.72±0.15(Predicted)
• CAS DataBase Reference: Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol(CAS DataBase Reference)
• NIST Chemistry Reference: Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol(185756-31-4)
• EPA Substance Registry System: Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol(185756-31-4)

Safety Data

• Hazardous Substances Data: 185756-31-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol is used as an emulsifier and stabilizer for enhancing the solubility and stability of active pharmaceutical ingredients. This improves the overall efficacy and quality of drug formulations.
Used in Cosmetic Industry:
In the cosmetic industry, sucrosofate is used as a viscosity increasing agent and emollient, providing a smoother texture and a more pleasant feel to cosmetic products.
Used in Antioxidant Applications:
Bis(4-hydroxybenzoyl)-1,4:3,6-dianhydrosorbitol is being studied for its potential antioxidant properties, which may contribute to health benefits, particularly in the treatment of inflammatory and skin disorders.

Upstream product

• 652-67-5 Isosorbide 
• 99-96-7 4-hydroxy-benzoic acid 
• 27914-73-4 4-acetoxybenzoyl chloride 
• 1337985-51-9 1,4:3,6-dianhydro-D-sorbitol-2,5-bis(4-acetoxybenzoate) 
• 2345-34-8 4-acetyloxy-benzoic acid 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 1486-51-7 p-(benzyloxy)benzoic acid 

Downstream Products

• 951768-66-4 C₃₂H₃₆Br₂O₁₀ 
• 256513-67-4 isosorbide 2,5-bis(4-acryloyloxy)benzoate 
• 1337985-50-8 1,4:3,6-dianhydro-D-sorbitol-2,5-bis(4-(4-acetoxybenzoyloxy)benzoate) 
• 201794-01-6 1,4:3,6-dianhydro-D-sorbitol-2,5-bis(4-(4-(hexyloxy)benzoyloxy)benzoate) 
• 197663-64-2 1,4:3,6-dianhydro-D-sorbitol-2,5-bis(4-(4-methoxybenzoyloxy)benzoate) 

Relevant articles and documents

Properties and structural coloured film preparation of some chiral dopants derived from D-Isosorbide

A series of chiral dopants derived from D-isosorbide were synthesized. Some of them exhibita monotropicsmecticA phase. Comparison of the melting points of these chiral dopants, the decrease of them is mainly driven by the large entropy change. The helical

A method for synthesis of chiral dopant H (by machine translation)

The invention belongs to the technical field of the chiral dopant, in particular relates to a method for synthesis of chiral dopant H. The synthesis method mainly comprises the following steps: isosorbide with hydroxy benzoic acid esterification reaction,

Polymerizable chiral compd.

The invention provides a polymerizable chiral compound which has strong HTP and is excellent in solubility. The polymerizable chiral compound shown in a general form (I) has strong HTP and a low melting point. As the melting point is low, the polymerizable chiral compound has excellent solubility with other liquid crystal compounds and is useful to be a composition material of polymerizable liquid crystal composition. In addition, as the polymerizable chiral compound has a strong torque force, the polymerizable chiral compound can be used to manufacture optical anisotropy of excellent optical properties. The optical anisotropy can be used in deflection plates, phase difference plates, selective reflection plates, etc.

POLYMERIZABLE CHIRAL COMPOUND

The present invention refers to, a strong HTP and a, a lower melting point as chiral compounds having a diffusion barrier it is an object to provide an 1/10 time as large as that of. Said liquid crystal aberration correcting element, general formula (I) Polymerizable chiral reagent represented by compound. Subject to the compounds of the invention herein having a melting and low HTP, since a color compound melting portion of the electron emitting material paste excellent drives liquid crystal composition, is useful as a components. Furthermore, as a component compound polymerizable chiral reagent of the invention herein a polymerizable liquid crystal composition, to produce large-sized content of compound polymerizable chiral reagent of the insertion part and the holder and having excellent optical characteristics and operating method of anisotropic body group represented by the formula 1.. A optically anisotropic product, of the invention herein, the deflecting plates, retardation plate and the like useful.

Optical Behaviors of Cholesteric Liquid-Crystalline Polyester Composites with Various Chiral Photochromic Dopants

New developments in the field of chiral nematic liquid crystals, such as color displays, are now being widely proposed. This article describes the tunable incident reflection band based on composite materials of low-molecular-weight chiroptical dopants an

Liquid crystal compositions, polymer networks derived therefrom and process for making the same

The invention relates to compounds of Formula (I): The invention further relates to liquid crystal compositions comprising compounds of Formula (I); compositions further comprising one or more chiral compounds; and polymer networks derived from the polymerization of the liquid crystal compositions. Another embodiment relates to processes for providing compounds of Formula (I).

BISPHENOL POLYMER STRUCTURAL UNITS AND METHOD OF MAKING THE SAME

Provided herein are isosorbide-based bisphenol polymer structural units and methods of making the same. These structural units may be polymerized with one or more other types of structural units to form polymers, such as polycarbonates.

Tuning helical twisting power of isosorbide-based chiral dopants by chemical modifications

Isosorbide-based chiral dopants (ICD) with various substituent groups were newly synthesized to control their helical twisting powers (HTP). Phase transition behaviors of ICD molecules were first investigated by combined techniques of differential scanning calorimetry, wide-angle X-ray diffraction, and cross-polarized optical microscopy. ICD with n-hexyloxy end groups formed the multiple ordered phases, and those with methoxy or acetoxy end groups exhibited a simple crystal-to-isotropic transition. Energy-minimized chemical conformations of ICD molecules revealed that all the ICDs had twisted conformations and that the extension of the benzoyl ester moiety induced a higher twisted conformation. By varying substitution groups, HTPs of ICDs were controlled from 26.6 to 80.μm-1. Particularly, ICD with an acetoxy end group (ICD-2) showed the largest HTP. It was also realized that by controlling the content of ICD-2 from 3.0 to 4.5mol%, the helical pitch length of cholesteric LC mixture was adjusted to reflect a specific visible light. Copyright Taylor & Francis Group, LLC.

CHIRAL COMPOUNDS, AND LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM

The invention relates to compounds of formula (I): insert Formula (I) here wherein R1and R2are each independently selected from the group: H, F, Cl and CH3; n1 and n2 are each independently integers 3 to 20; q and r are each independently integers 0, 1 or 2, with the proviso that q + r is ≥ 1; D is a divalent chiral radical selected from the group: (D1-D4) wherein R3 is a C1 to C6 straight or branched chain alkyl group; and each B1and B2 is a divalent radical independently selected from the group: R4-substituted-1,4-phenyl, wherein R4 is H,-CH3 or -OCH3, 2,6-naphthyl; and 4,4'-biphenyl; with the provisos that when q + r = 3, at least one of B1 and B2 is R4-substituted-1,4-phenyl; and when q + r = 4, at least two of B1 and B2 are R4-substituted-1,4-phenyl. The invention further relates to liquid crystal compositions comprising compounds of formula (I) and polymer networks derived from the polymerization of the liquid crystal compositions.

Process for the preparation of dianhydrohexitol bisacylates

The invention relates to a process for the preparation of dianhydrohexitol bisacylates of the general formula (2), in which free dihydrohexitols are esterified with aromatic, hydroxyl-substituted carboxylic acids of the general formula (3), HO—CO—X—OH??(3