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CAS

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186023-44-9

Fmoc-Ala-Pro-OH is a synthetic tripeptide consisting of three amino acids: phenylalanine (Fmoc), alanine (Ala), and proline (Pro). It features an Fmoc-protected amine group and a terminal carboxylic acid, which can be deprotected under basic conditions to reveal the free amine for further conjugations. The terminal carboxylic acid can be reacted with primary amine groups using activators like EDC or HATU to form stable amide bonds, making it a versatile building block in peptide synthesis and conjugation.

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  • 186023-44-9 Structure

  • Basic information

    1. Product Name: Fmoc-Ala-Pro-OH
    2. Synonyms: Fmoc-Ala-Pro-OH
    3. CAS NO:186023-44-9
    4. Molecular Formula:
    5. Molecular Weight: 408.454
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 186023-44-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Fmoc-Ala-Pro-OH(CAS DataBase Reference)
    10. NIST Chemistry Reference: Fmoc-Ala-Pro-OH(186023-44-9)
    11. EPA Substance Registry System: Fmoc-Ala-Pro-OH(186023-44-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 186023-44-9(Hazardous Substances Data)

186023-44-9 Usage

Uses

Used in Pharmaceutical Industry:
Fmoc-Ala-Pro-OH is used as a building block for the synthesis of various peptides and peptide-based drugs. Its Fmoc-protected amine and terminal carboxylic acid allow for the controlled assembly of complex peptide structures, which can be utilized in the development of therapeutic agents targeting a wide range of diseases.
Used in Research and Development:
In the field of research, Fmoc-Ala-Pro-OH serves as a valuable tool for studying peptide-protein interactions, enzyme substrate specificity, and the development of novel bioactive molecules. Its ability to form stable amide bonds with primary amine groups makes it an ideal candidate for creating conjugates with various biomolecules, such as antibodies, for use in immunoassays and drug delivery systems.
Used in Chemical Synthesis:
Fmoc-Ala-Pro-OH is used as a key intermediate in the synthesis of more complex peptides and peptidomimetics. Its unique structure and functional groups enable the creation of diverse peptide derivatives with tailored properties, which can be applied in various fields, including drug discovery, materials science, and biotechnology.
Used in Drug Delivery Systems:
Fmoc-Ala-Pro-OH can be employed in the design of targeted drug delivery systems, where its ability to form stable amide bonds with primary amine groups on drug molecules or carriers can be exploited to enhance the specificity and efficacy of therapeutic agents. This can lead to improved drug targeting, reduced side effects, and increased patient compliance.

Check Digit Verification of cas no

The CAS Registry Mumber 186023-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,0,2 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 186023-44:
(8*1)+(7*8)+(6*6)+(5*0)+(4*2)+(3*3)+(2*4)+(1*4)=129
129 % 10 = 9
So 186023-44-9 is a valid CAS Registry Number.

186023-44-9Upstream product

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