TBAI/K2S2O8-facilitated reaction of sulfonylhydrazides with alkynes: Facile synthesis of (E)-β-iodovinyl sulfones
An efficient and convenient approach for the construction of various (E)-β-iodovinyl sulfones has been developed through potassium persulfate/tetrabutylammonium iodide-facilitated reaction of sulfonylhydrazides with alkynes. The products were obtained in good to excellent yields. The salient features of this reaction are the applications of a new iodine source, environmentally benign, safer solid oxidant, and shorter reaction time.
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