186268-07-5

Basic information

• Product Name: 6-Methyl-7-nitro-5-(pyrrolidin-1-ylmethyl)quinoxaline-2,3(1H,4H)-dione
• Synonyms: PD-161989
• CAS NO: 186268-07-5
• Molecular Formula: C₁₄H₁₆N₄O₄
• Molecular Weight: 304.30802
• Mol File: 186268-07-5.mol

Chemical Properties

• CAS DataBase Reference: 6-Methyl-7-nitro-5-(pyrrolidin-1-ylmethyl)quinoxaline-2,3(1H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methyl-7-nitro-5-(pyrrolidin-1-ylmethyl)quinoxaline-2,3(1H,4H)-dione(186268-07-5)
• EPA Substance Registry System: 6-Methyl-7-nitro-5-(pyrrolidin-1-ylmethyl)quinoxaline-2,3(1H,4H)-dione(186268-07-5)

Safety Data

• Hazardous Substances Data: 186268-07-5(Hazardous Substances Data)

Relevant articles and documents

Cyclic amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists

A novel series of substituted quinoxaline 2,3-diones useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate antagoni

CYCLIC AMINE DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONES AS GLUTAMATE RECEPTOR ANTAGONISTS

A novel series of substituted quinoxaline 2,3-diones of Formula I STR1 useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate antagonists and are useful in the treatment of stroke, cerebral ischemia, or cerebral infarction resulting from thromboembolic or hemorrhagic stroke, cerebral vasospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia, seizure disorders, pain, Alzheimer's, Parkinson's, and Huntington's Diseases.