The Synthesis of Functionalized Pyrrolo-[2,1-c][1,4]-Benzodiazepines
Two concise and high yielding routes to the antitumour antibiotic pyrrolo-[2,1-c][1,4]-benzodiazepine ring system are described. Thus, condensation of prolinol with 2-azidobenzoylchloride gives the tertiary amide (3). Oxidation to the aldehyde (4) followe
O'Neil, Ian A.,Murray, Clare L.,Hunter, Rachel C.,Kalindjian, S. Barret,Jenkins, Terry C.
p. 75 - 78
(2007/10/03)
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