187753-15-7

Basic information

• Product Name: 2-Piperidinecarboxylicacid,4-oxo-,methylester(9CI)
• Synonyms: 2-Piperidinecarboxylicacid,4-oxo-,methylester(9CI);Methyl 4-oxopiperidine-2-carboxylate;4-Oxo-piperidine-2-carboxylic acid methyl ester
• CAS NO: 187753-15-7
• Molecular Formula: C7H11NO3
• Molecular Weight: 157.17
• Product Categories: CARBOXYLICESTER
• Mol File: 187753-15-7.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: 2-Piperidinecarboxylicacid,4-oxo-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinecarboxylicacid,4-oxo-,methylester(9CI)(187753-15-7)
• EPA Substance Registry System: 2-Piperidinecarboxylicacid,4-oxo-,methylester(9CI)(187753-15-7)

Safety Data

• Hazardous Substances Data: 187753-15-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Piperidinecarboxylic acid, 4-oxo-, methyl ester (9CI) is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the formation of complex molecular structures that can exhibit therapeutic effects.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, 2-Piperidinecarboxylic acid, 4-oxo-, methyl ester (9CI) serves as a key intermediate, facilitating the creation of diverse organic compounds that can have a range of applications, from materials science to specialty chemicals.
Used in Medicinal Chemistry and Drug Discovery:
Due to its unique structural properties, 2-Piperidinecarboxylic acid, 4-oxo-, methyl ester (9CI) is utilized in medicinal chemistry and drug discovery processes, where it may contribute to the development of new therapeutic agents with novel mechanisms of action.
Used in Research and Development:
In research and development settings, 2-Piperidinecarboxylic acid, 4-oxo-, methyl ester (9CI) is employed as a compound of interest for studying its chemical behavior and potential applications in creating new molecules with specific biological activities.

Upstream product

• 81357-18-8 4-oxo-piperidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 

Downstream Products

• 1799811-83-8 1-(tert-butyl)-2-methyl-(S)-4-oxopiperidine-1,2-dicarboxylate 
• 1259011-96-5 (±)-methyl 1-benzyloxycarbonyl-4,4-difluoropiperidine-2-carboxylate 

Relevant articles and documents

PHENOXYETHYL CYCLIC AMINE DERIVATIVES AND THEIR ACTIVITY AS EP4 RECEPTOR MODULATORS

The present invention provides a compound of the Formula (I): wherein X, R, R1,R2,R3, R4,R5,R6, R7, R8, and R9 are as defined herein, or a pharmaceutically acceptable salt thereof.

AMINO ACID DERIVATIVES

There is provided amino acid derivatives of formula I, wherein p, q, R 1, R 2, R 3, R 4, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

A new synthesis of (2S)-4-oxopipecolic acid by thermal rearrangement of enantiopure spirocyclopropaneisoxazolidine

A novel synthesis of (2S)-4-oxo-pipecolic acid is reported. The synthetic route employs as a key step the diastereoselective cycloaddition of the N- glycosylnitrone 7 to methylenecyclopropane followed by thermal rearrangement of the spirocyclopropaneisoxazolidine 8a. Stereoselective reduction of the N- BOC methyl ester of 4-oxopipecolic acid by L-selectride gives the protected cis-4-hydroxy-pipecolic acid 14.