187795-98-8

Basic information

• Product Name: N-{2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl}pyridin-2-amine
• CAS NO: 187795-98-8
• Molecular Formula: C₂₀H₂₆N₄O₂
• Molecular Weight: 354.446
• Mol File: 187795-98-8.mol

Chemical Properties

• Boiling Point: 551.899°C at 760 mmHg
• Flash Point: 287.578°C
• Density: 1.219g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: N-{2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl}pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-{2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl}pyridin-2-amine(187795-98-8)
• EPA Substance Registry System: N-{2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl}pyridin-2-amine(187795-98-8)

Safety Data

• Hazardous Substances Data: 187795-98-8(Hazardous Substances Data)

Relevant articles and documents

Process for synthesizing N-aryl piperazines with chiral N'-1-[benzoyl(2-pyridyl)amino]-2-propane substitution

A process for formation of N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane side-chains having the structure shown in formula below, and for making intermediate compounds therefor. In this process, chirality is introduced at the piperazine ring formation step and 2-aminopyridyl substitution is incorporated via displacement. The resulting N, N′ disubstituted piperazines act on the central nervous system at 5HT receptors.

Process for synthesizing N-aryl piperazines with chiral N'-1-[benzoyl(2-pyridyl)amino]-2-propane substitution

A process for formation of N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane side-chains having the structure shown in formula below, and for making intermediate compounds therefor. In this process, chirality is introduced at the piperazine ring formation step and 2-aminopyridyl substitution is incorporated via displacement. The resulting N,N′ disubstituted piperazines act on the central nervous system at 5HT receptors.