188030-43-5

Basic information

• Product Name: N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE
• Synonyms: N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE;Alanine, N-[(1,1-dimethylethoxy)carbonyl]-3,3,3-trifluoro-
• CAS NO: 188030-43-5
• Molecular Formula: C₈H₁₂F₃NO₄
• Molecular Weight: 243.18
• Mol File: 188030-43-5.mol

Chemical Properties

• Boiling Point: 303.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.319±0.06 g/cm3(Predicted)
• PKA: 2.37±0.10(Predicted)
• CAS DataBase Reference: N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE(188030-43-5)
• EPA Substance Registry System: N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE(188030-43-5)

Safety Data

• Hazardous Substances Data: 188030-43-5(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE is used as a building block in the synthesis of peptides and other pharmaceutical agents for its unique properties that make it valuable in the development of novel drug candidates.
Used in Drug Development:
N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE is used as a key component in the creation of new pharmaceuticals, leveraging its highly fluorinated nature to enhance the properties of drug molecules.
Safety Considerations:
It is important to handle N-(TERT-BUTOXYCARBONYL)-3,3,3-TRIFLUOROALANINE with care, following proper safety protocols and procedures, due to its potentially hazardous nature.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 17463-43-3 3,3,3-trifluoro-DL-alanine 

Downstream Products

• 672959-90-9 tert-butyl [1-(2-methylphenylcarbamoyl)-1-trifluoromethyl-methyl]-carbamate 
• 1403943-20-3 tert-butyl 1,1,1-trifluoro-3-oxo-3-(2-(phenylcarbamoyl)-1H-pyrrol-1-ylamino)propan-2-ylcarbamate 
• 126536-02-5 (2,2,2-trifluoro-1-hydroxymethylethyl)carbamic acid tert-butyl ester 

Relevant articles and documents

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Compounds having a structure of Formula (IX) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1----Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.

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