188182-79-8

Basic information

• Product Name: ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE
• Synonyms: ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE;Ethyl 3-(2-fluoro-4-methoxyphenyl)-3-oxopropanoate
• CAS NO: 188182-79-8
• Molecular Formula: C12H13FO4
• Molecular Weight: 240.2276232
• Mol File: 188182-79-8.mol

Chemical Properties

• Boiling Point: 319.4±27.0 °C(Predicted)
• Appearance: /
• Density: 1.188±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 10.52±0.48(Predicted)
• CAS DataBase Reference: ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE(188182-79-8)
• EPA Substance Registry System: ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE(188182-79-8)

Safety Data

• Hazardous Substances Data: 188182-79-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE is used as a key intermediate in the synthesis of various drugs. Its unique structure, including the fluorine and methoxy substituents, allows for the development of compounds with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability.
Used in Agrochemical Industry:
In the agrochemical sector, ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE is utilized as an intermediate for the production of agricultural products. Its incorporation into the molecular structures of these products can lead to the creation of more effective and targeted agrochemicals, contributing to improved crop protection and yield.
Used in Medicinal Chemistry Research:
ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE is employed as a valuable building block in medicinal chemistry research. Its presence in the synthesis of new compounds allows for the exploration of novel therapeutic agents with potential applications in various disease areas, including infectious diseases, neurological disorders, and cancer.
Used in the Development of New Compounds with Potential Applications:
Due to its unique structural features, ETHYL 2-FLUORO-4-METHOXYBENZOYLACETATE is used in the development of new compounds with potential medicinal and agricultural applications. Its versatility as a synthetic intermediate enables the creation of a wide range of molecules with diverse biological activities, expanding the scope of available treatments and products in both industries.

Upstream product

• 74457-86-6 1-(2-fluoro-4-methoxyphenyl)-1-ethanone 
• 321-24-4 2-Fluor-4-methoxybenzoesaurechlorid 
• 6148-64-7 ethyl potassium malonate 

Relevant articles and documents

PYRAZOLOPYRIDINE DERIVATIVES AS ANTICANCER AGENT

The present invention concerns compounds of following general formula (I): (Formula I) and their pharmaceutically acceptable salts, their method of preparation and their uses, notably as anticancer agent.

Herbicidal phenylmethoxphenyl heterocycles

Novel herbicidal compounds, compositions containing them, and methods for their use in controling weeds are disclosed. The novel herbicidal compounds are optionally substituted phenylmethoxy or phenylmethylthio heterocycles of the formula: STR1 in which Q is selected from: STR2 R=halogen; R1 =lower alkyl, lower alkoxy, lower haloalkyl, lower haloalkoxy, lower alkylthio, lower sulfonyl, or lower alkylsulfinyl; R2 =lower alkyl, or lower haloalkyl; X=H, halogen, or lower alkyl; W=O or S; Z, Z1, Z2 are independently selected from H, halogen, straight or branched chain lower alkyl, lower alkoxy, is lower haloalkoxy, cyano, lower cyanoalkyloxy, or aryl; or Z and Z1 are adjacent to each other on the benzene ring, and taken together are --(CH2)4 --; or Z2 is OA in the 2-, 3-, or 4-position of the phenyl ring; A is a derivative of an alkanoate bonded to the phenoxy oxygen at the alpha carbon; R3 is H or lower alkyl; R4 =OH or an agriculturally acceptable salt thereof, straight or branched chain lower alkoxy, lower haloalkoxy, alkoxyalkoxy, alkoxyalkoxyalkoxy, amino, lower alkylamino, lower alkylsulfonylamino, or lower (alkyl)(alkylsulfonyl)amino; and R5 =halogen or lower alkyl ester.