188199-78-2

Basic information

• Product Name: 3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE
• Synonyms: 3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE;3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE, 95+%
• CAS NO: 188199-78-2
• Molecular Formula: C₁₀H₁₂O₅
• Molecular Weight: 212.2
• Mol File: 188199-78-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE(188199-78-2)
• EPA Substance Registry System: 3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE(188199-78-2)

Safety Data

• Hazardous Substances Data: 188199-78-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to create complex organic compounds.
Used in Pesticide Industry:
3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE is used as a building block in the production of pesticides, contributing to the development of effective and efficient pest control agents.
Used in Dye Industry:
3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE is used in the production of dyes, enabling the creation of a wide range of colorants for various applications.
Used in Organic Synthesis:
3,5-DIMETHOXYPHENYLGLYOXAL HYDRATE is used as a versatile building block in organic synthesis to create complex organic compounds for various applications across different industries.

Upstream product

• 39151-19-4 1-(3,5-dimethoxyphenyl)ethan-1-one 
• 17213-59-1 2-diazo-1-(3,5-dimethoxyphenyl)ethanone 

Downstream Products

• 312583-37-2 4⁽⁵⁾-(3,5-dimethoxyphenyl)-1H-imidazole 
• 188199-81-7 2-carbomethoxy-4⁽⁵⁾-(3',5'-dimethoxyphenyl)imidazole 
• 312583-36-1 4-(3',5'-dimethoxyphenyl)-1-(1-tetrahydrofuranyl)imidazole 
• 188199-84-0 1-(2'-tetrahydrofuranyl)-2-hydroxymethyl-4⁽⁵⁾-(3'',5''-dimethoxyphenyl)imidazole 
• 188199-83-9 1-(2'-tetrahydrofuranyl)-2-carbomethoxy-4⁽⁵⁾-(3'',5''-dimethoxyphenyl)imidazole 
• 222991-30-2 1-(2'-tetrahydropyranyl)-2-hydroxymethyl-4⁽⁵⁾-(3'',5''-dimethoxyphenyl)imidazole 
• 222991-29-9 1-(2'-tetrahydropyranyl)-2-carbomethoxy-4⁽⁵⁾-(3'',5''-dimethoxyphenyl)imidazole 
• 188199-85-1 1-(2'-tetrahydrofuranyl)-2-trichloroacetimidoxymethyl-4⁽⁵⁾-(3'',5''-dimethoxyphenyl)imidazole 
• 150250-95-6 L-733,725 

Relevant articles and documents

COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES

Embodiments are directed to therapeutic, diagnostic, or functional complexes comprising a kethoxal derivative.

Highly chemoselective trichloroacetimidate-mediated alkylation of ascomycin: A convergent, practical synthesis of the immunosuppressant L- 733,725

L-733,725, a new immunosuppressant drug candidate, was prepared by a highly chemoselective alkylation of the macrolide ascomycin at the C32 hydroxy position with the imidazolyl trichloroacetimidate 16. The trichloroacetimidate-activated side chain 16 was prepared by an efficient fourstep sequence in 42% overall yield. The high chemoselectivity in the alkylation of the C32 hydroxy group of the unprotected ascomycin was the result of the synergetic effects of the electron-donating protecting group on the imidazole 16, the polar, moderately basic solvent, and the strong acid catalyst. N,N-Dimethylpivalamide mixed with acetonitrile was found to be the best solvent and trifluromethanesulfonic acid the best catalyst. This synthesis coupled with a resin column purification of L-733,725 followed by crystallization of its tartrate salt has been used to make multikilogram quantities of the bulk drug with consistent and high purity.