1,2-Benzothiazine 1,1-dioxide P2-P3 peptide mimetic aldehyde calpain I inhibitors
A series of peptide mimetic aldehyde inhibitors of calpain I was prepared in which the P2 and P3 amino acids were replaced by substituted 3,4-dihydro-1,2-benzothiazine-3-carboxylate 1,1-dioxides. The effect of 2, 6, and 7-benzothiazi
Wells,Tao,Josef,Bihovsky
p. 3488 - 3503
(2007/10/03)
BENZOTHIAZO AND RELATED HETEROCYCLIC GROUP-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS
The present invention is directed to novel benzothiazo and related heterocyclic group-containing inhibitors of cysteine or serine proteases. Methods for using the same are also described.
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(2008/06/13)
Reaction of m-Phenylenebisdiazonium Salts with Unsaturated Compounds
Main route of the reaction between m-phenylenebisdiazonium tetrafluoroborate with unsaturated compounds (acrylonitrile, styrene, alkyl acrylates and methacrylates) in the presence of NaCl and a catalyst (CuCl2) is the Meerwein chloroarylation by one diazogroup; the second diazogroup is replaced by chlorine according to Sandmayer's reaction.
Obushak,Ganushchak,Lesyuk,Pil'o,Demchuk,Mazyar
p. 432 - 435
(2007/10/03)
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