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188622-47-1

6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 188622-47-1 Structure

  • Basic information

    1. Product Name: 6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione
    2. Synonyms: 6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione
    3. CAS NO:188622-47-1
    4. Molecular Formula: C13H5ClFNO2
    5. Molecular Weight: 261.638
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 188622-47-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione(188622-47-1)
    11. EPA Substance Registry System: 6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione(188622-47-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 188622-47-1(Hazardous Substances Data)

188622-47-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 188622-47-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,6,2 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 188622-47:
(8*1)+(7*8)+(6*8)+(5*6)+(4*2)+(3*2)+(2*4)+(1*7)=171
171 % 10 = 1
So 188622-47-1 is a valid CAS Registry Number.

188622-47-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Chloro-9-fluorobenz[9]isoquinoline-5,10-dione

1.2 Other means of identification

Product number -
Other names 6-chloro-9-cyclopropyl-9h-purine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:188622-47-1 SDS

188622-47-1Relevant articles and documents

Synthesis and biological evaluation of new cytotoxic indazolo[4,3-gh] isoquinolinone derivatives

Shahabi, Manochehr,Schirmer, Eva,Shanab, Karem,Leepasert, Theerachart,Ruzicka, Jana,Holzer, Wolfgang,Spreitzer, Helmut,Aicher, Babette,Schmidt, Peter,Blumenstein, Lars,Müller, Gilbert,Günther, Eckhard

, p. 1846 - 1852 (2013/04/10)

A series of indazolo[4,3-gh]isoquinolinones derivatives have been synthesized to decrease cardiotoxic side effects in comparison to Mitoxantrone. The antiproliferative effects of different side chains were investigated and tested on at least four different cell lines of cervix, ovarian, CNS, NSCLC (non-small-cell lung cancer) and colon carcinoma. In addition to antiproliferative activities, influence on cell cycle and intercalation behavior have been tested.

Synthesis of regioisomeric 6,9-(chlorofluoro)-substituted benzo[g]quinoline-5,10-diones, benzo[g]isoquinoline-5,10-diones and 6-chloro-9-fluorobenzo[g]quinoxaline-5,10-dione

Krapcho, A. Paul,Gallagher, Cynthia E.,Hammach, Abdelhakim,Ellis, Michael,Menta, Ernesto,Oliva, Ambrogio

, p. 27 - 32 (2007/10/03)

Treatment of difluoro or chloro fluoro-substituted benzyl bromides 5a-c with zinc dust in tetrahydrofuran leads to the corresponding benzylic zinc bromides 6a-c. These organometallics on treatment with chlorosubstituted heterocyclic esters 4A and 4B mediated by nickel catalysis undergo couplings to yield dihalobenzyl substituted heterocyclic esters 7Aa-c and 7Ba-c. Treatment of 4c with 6c under Pd catalysis leads to 7Cc. The acids 8, prepared by hydrolysis of these esters, with treatment of fuming sulfuric acid undergo cyclizations and oxidations to yield the desired regioisomeric dihalo-substituted heterocyclic quinones 2.

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